| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
C1orf187 |
| Specificity: |
This antibody reacts specifically with C1orf187 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human C1orf187 |
| Gene ID: |
374946 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
C1orf187 acts as a chemorepulsive guidance protein and directs commissural axons during development by repelling neurite outgrowth from the spinal cord, C1orf187 inhibits outgrowth from the olfactory bulb and likely contributes to the formation of the lateral olfactory tract, C1orf187 modulates neural crest migration by reducing the polarization of these cells, Dorsal repulsive axon guidance protein and Neucrin, During development, It acts as an antagonist of the Wnt signaling pathway by inhibiting the stabilization of cytosolic Î, also known as Draxin, is a 349 amino acid secreted protein that is required of the development of the spinal cord and forebrain commissures, leading to a net decrease in migrational distance, leading to reduced velocity of migration and increased frequency of changing direction, ², -catenin via its interaction with LRP6, C1orf187 |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
FLJ34999 Draxin Neucrin |
| Also known as: |
C1orf187 Polyclonal Antibody |
| Other name: |
Anti-C1orf187 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
C1orf187 |
| Short name: |
Anti-C1orf187 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-C1orf187 (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
25054 |
| Gene: |
DRAXIN |
More about : DRAXIN |
| Long gene name: |
dorsal inhibitory axon guidance protein |
| Synonyms gene: |
C1orf187 |
| Synonyms gene name: |
chromosome 1 open reading frame 187 |
| Synonyms name: |
dorsal repulsive axon guidance protein neural tissue-specific cysteine-rich protein |
| Locus: |
1p36, 22 |
| Discovery year: |
2005-08-12 |
| GenBank acession: |
AY358750 |
| Entrez gene record: |
374946 |
| Pubmed identfication: |
19150847 |
| RefSeq identity: |
NM_198545 |
| Havana BLAST/BLAT: |
OTTHUMG00000002227 |