| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
C1orf146 |
| Specificity: |
This antibody reacts specifically with C1orf146 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human C1orf146 |
| Gene ID: |
388649 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
A breakpoint has been identified in 1q which disrupts the DISC1 gene and is linked to schizophrenia, Aberrations in chromosome 1 are found in a variety of cancers including head and neck cancer, Gaucher disease and Usher syndrome are also associated with chromosome 1, Notably, Parkinsons, Stickler syndrome, The C1orf146 gene product has been provisionally designated C1orf146 pending further characterization, The MUTYH gene is located on chromosome 1 and is partially responsible for familial adenomatous polyposis, The mechanism of rapidly enhanced aging is unclear and is a topic of continuing exploration, There are about 3, When defective, and considering the great number of genes there are also a large number of diseases associated with chromosome 1, malignant melanoma and multiple myeloma, the LMNA gene product can build up in the nucleus and cause characteristic nuclear blebs, the rare aging disease Hutchinson-Gilford progeria is associated with the LMNA gene which encodes lamin A, 000 genes on chromosome 1, Chromosome 1 is the largest human chromosome spanning about 260 million base pairs and making up 8% of the human genome |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Also known as: |
C1orf146 Polyclonal Antibody |
| Other name: |
Anti-C1orf146 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
C1orf146 |
| Short name: |
Anti-C1orf146 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-C1orf146 (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
24032 |
| Gene: |
C1orf146 |
More about : C1orf146 |
| Long gene name: |
chromosome 1 open reading frame 146 |
| Locus: |
1p22, 1 |
| Discovery year: |
2005-07-11 |
| Entrez gene record: |
388649 |
| Pubmed identfication: |
15496913 |
| RefSeq identity: |
NM_001012425 |
| Havana BLAST/BLAT: |
OTTHUMG00000010285 |