| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
IL-6R Beta/CD130/gp130 |
| Specificity: |
This antibody reacts specifically with IL-6R Beta/CD130/gp130 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Subcellular locations: |
Cytoplasm |
| Antigen Source: |
KLH conjugated synthetic peptide derived from mouse IL6R beta |
| Gene ID: |
16195 |
| Swiss Prot: |
Q00560 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Binds to IL6/IL6R (alpha chain) complex, CNTF, CTF1 and BSF3 can utilize gp130 for initiating signal transmission, Does not bind IL6, IL11, LIF, May have a role in embryonic development, OSM, The receptor systems for IL6, and transduces the signal, resulting in the formation of high-affinity IL6 binding sites, Signal-transducing molecule |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
GP130 CD130 |
| Also known as: |
IL-6R Beta/CD130/gp130 Antibody |
| Other name: |
Anti-IL-6R Beta/CD130/gp130 |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Gene target: |
IL-6R Beta/CD130/gp130 |
| Short name: |
Fluor 594, Anti-IL-6R Beta/CD130/gp130 |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-Interleukin-6R b/CD130/gp130 |
| Identity: |
6021 |
| Gene: |
IL6ST |
More about : IL6ST |
| Long gene name: |
interleukin 6 signal transducer |
| Synonyms gene name: |
interleukin 6 signal transducer (gp130, oncostatin M receptor) |
| Synonyms name: |
gp130, oncostatin M receptor Interleukin-6 receptor subunit beta |
| Locus: |
5q11, 2 |
| Discovery year: |
1991-08-12 |
| GenBank acession: |
M57230 |
| Entrez gene record: |
3572 |
| Pubmed identfication: |
2261637 |
| RefSeq identity: |
NM_002184 |
| Classification: |
CD molecules Fibronectin type III domain containing Interleukin receptors |
| Havana BLAST/BLAT: |
OTTHUMG00000097043 |