| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
Jab1 |
| Specificity: |
This antibody reacts specifically with Jab1 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human Jab1 |
| Gene ID: |
10987 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
COP9 signalosome has been shown to interact with SCF-type E3 ubiquitin ligases and act as a positive regulator of E3 ubiquitin ligases, It is also known to be an coactivator that increases the specificity of JUN/AP1 transcription factors, The structure and function of COP9 signalosome is similar to that of the 19S regulatory particle of 26S proteasome, This protein is reported to be involved in the degradation of cyclin-dependent kinase inhibitor CDKN1B/p27Kip1, a highly conserved protein complex that functions as an important regulator in multiple signaling pathways, The protein encoded by this gene is one of the eight subunits of COP9 signalosome |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
JAB1 SGN5 MOV-34 CSN5 |
| Also known as: |
Jab1 Polyclonal Antibody |
| Other name: |
Anti-Jab1 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
Jab1 |
| Short name: |
Anti-Jab1 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-Jab1 (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
2240 |
| Gene: |
COPS5 |
More about : COPS5 |
| Long gene name: |
COP9 signalosome subunit 5 |
| Synonyms gene name: |
Arabidopsis, COP9 (constitutive photomorphogenic, homolog) subunit 5 COP9 constitutive photomorphogenic homolog subunit 5 (Arabidopsis) |
| Locus: |
8q13, 1 |
| Discovery year: |
2000-06-08 |
| GenBank acession: |
U65928 |
| Entrez gene record: |
10987 |
| Pubmed identfication: |
8837781 9341143 |
| Classification: |
COP9 signalosome |
| Havana BLAST/BLAT: |
OTTHUMG00000164563 |