| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
Vinexin |
| Specificity: |
This antibody reacts specifically with Vinexin |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human Vinexin |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Although Vinexin alpha and Vinexin beta have different roles within the cell, Like Vinexin alpha, Localized to cell junctions in both the cytoplasm and the cytoskeleton, Together, Vinexin alpha and Vinexin beta are involved in cell-cell adhesion, Vinexin alpha functions to promote Actin stress fiber formation, Vinexin beta is localized to cell junctions in the cytoplasm, both proteins contain three SH3 domains in their carboxy terminus and are expressed in a variety of tissues, brain, but is also found in the nucleus where it plays an important role in cell spreading and in activation of the JNK pathway in response to EGF stimulation, designated Vinexin alpha and Vinexin beta, heart, including placenta, liver, pancreas and skeletal muscle, playing an important role in modification of the Actin cytoskeleton, signal transduction and cytoskeletal organization throughout the cell, Vinexin is a 671 amino acid protein that is expressed as two isoforms |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
SCAM-1 SH3D4 vinexin |
| Also known as: |
Vinexin Polyclonal Antibody |
| Other name: |
Anti-Vinexin Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
Vinexin |
| Short name: |
Anti-Vinexin (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-Vinexin (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
30907 |
| Gene: |
SORBS3 |
More about : SORBS3 |
| Long gene name: |
sorbin and SH3 domain containing 3 |
| Locus: |
8p21, 3 |
| Discovery year: |
2005-09-28 |
| Entrez gene record: |
10174 |
| Pubmed identfication: |
9885244 12510380 |
| RefSeq identity: |
NM_005775 |
| Havana BLAST/BLAT: |
OTTHUMG00000131728 |