| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
1, Connexin 31 |
| Specificity: |
1, This antibody reacts specifically with Connexin 31 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
1, KLH conjugated synthetic peptide derived from human Connexin 31 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Connexin 31, Connexin proteins share a common topology of four transmembrane ?helical domains, Cx31, Down-regulation of the connexin 31, Expression of connexin 31, Many of the key functional differences arise from specific amino acid substitutions in the most highly conserved domains, a cytoplasmic loop and cytoplasmic N- and C-termini, called connexons, is a 271 amino acid protein that is predominantly expressed in skin with lower expression in testis, that facilitate movement of low molecular weight proteins between cells via gap junctions, the transmembrane and extracellular regions, two extracellular loops, 1, 1 gene correlates with head and neck squamous cell carcinomas (HNSCC) and therefore it may be a potential therapeutic target, 1 is required for normal placental development in mice, 1 or Gap junction beta-5 protein, The connexin family of proteins form hexameric complexes |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
CX31, 1 |
| Also known as: |
1 Polyclonal Antibody, Connexin 31 |
| Other name: |
1 Polyclonal, Anti-Connexin 31 |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
1, Connexin 31 |
| Short name: |
1 (Polyclonal) Fluor 594, Anti-Connexin 31 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, 1 (polyclonal), antibody to-Connexin 31 |
| Alternative technique: |
polyclonals |
| Identity: |
4287 |
| Gene: |
GJB5 |
More about : GJB5 |
| Long gene name: |
gap junction protein beta 5 |
| Synonyms gene name: |
31, beta 5, beta 5 (connexin 31, beta 5 gap junction protein, gap junction protein, 1) gap junction protein, 1kDa |
| Synonyms name: |
connexin 31, 1 |
| Locus: |
1p34, 3 |
| Discovery year: |
1998-08-06 |
| GenBank acession: |
BC004379 |
| Entrez gene record: |
2709 |
| Pubmed identfication: |
9843209 |
| RefSeq identity: |
NM_005268 |
| Classification: |
Gap junction proteins |
| Havana BLAST/BLAT: |
OTTHUMG00000004053 |