| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
LAP2 alpha |
| Specificity: |
This antibody reacts specifically with LAP2 alpha |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human LAP2 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Î, Î, Alternative splicing produces six isoforms (Î, LAP2 also contains a unique DNA-binding amino-terminal domain, LAP2 is a nuclear envelope protein and contains an amino-terminal region called the LAP2-emerin-MAN1 or LEM motif, LAP2Î, LAP2Î, LAP2Î, Lamina-associated polypeptide 2 (LAP2) is also known as thymopoietin, The gene encoding human LAP2 maps to chromosome 12q23, The nuclear lamina contains intermediate filament-type proteins called lamins that form a dense network to strengthen and stabilize the nuclear envelope, also binds to lamin B, and Î, and LAP2Î, associate with chromosomal barrier-to-autointegration factor (BAF) and may play a role in stabilizing chromatin structure, is a non-membrane isoform of LAP2 that associates with the internal nucleoskeleton and binds lamin A, nuclear pore complexes and the nuclear lamina, Î, ´, µ, ±, ±, ±, ², ², ², ³, ) of mammalian LAP2 and three isoforms in Xenopus LAP2, 1, The nuclear envelope separates the nucleoplasm from the cytoplasm in eukaryotic cells and includes the outer and inner nuclear membrane |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
LAP2 |
| Also known as: |
LAP2 alpha Polyclonal Antibody |
| Other name: |
Anti-LAP2 alpha Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
LAP2 alpha |
| Short name: |
Anti-LAP2 alpha (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-LAP2 a (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
15842 |
| Gene: |
ERBIN |
More about : ERBIN |
| Long gene name: |
erbb2 interacting protein |
| Synonyms gene: |
ERBB2IP |
| Synonyms gene name: |
erbb2-interacting protein |
| Synonyms name: |
densin-180-like protein ERBB2-interacting protein |
| Locus: |
5q12, 3 |
| Discovery year: |
2001-06-18 |
| Entrez gene record: |
55914 |
| Pubmed identfication: |
10574462 10878805 |
| RefSeq identity: |
NM_018695 |
| Classification: |
PDZ domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000097808 |