| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
SAM68 |
| Specificity: |
This antibody reacts specifically with SAM68 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human SAM68 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Also like Sam 68, Fyn and Ras GAP, Fyn or Ras GAP, Like Sam 68, Originally cloned as Ras GAP-associated p62, PLC ?, PLC ?, SLM-1 and SLM-2, SLM-1 is tyrosine phosphorylated and functions as an adapter protein for signaling molecules, SLM-2 is not tyrosine phosphorylated, Sam 68 also associates with several SH2 and SH3 domain-containing signaling proteins, demonstrate RNA binding activity, further investigations have shown that Sam 68 and Ras GAP-associated p62 are not antigenically related, including GRB2, indicating that SLM-2 may not be an adapter protein for these proteins, nor are they encoded by the same gene, nor does it appear to associate with GRB2, such as GRB2 and PLC ?, the Sam 68-like mammalian proteins, Sam 68 is a protein that is phosphorylated on tyrosine and functions as a substrate for Src family tyrosine kinases during mitosis |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
Sam68 p62 FLJ34027 |
| Also known as: |
SAM68 Polyclonal Antibody |
| Other name: |
Anti-SAM68 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
SAM68 |
| Short name: |
Anti-SAM68 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-SAM68 (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
18116 |
| Gene: |
KHDRBS1 |
More about : KHDRBS1 |
| Long gene name: |
KH RNA binding domain containing, signal transduction associated 1 |
| Synonyms name: |
GAP-associated tyrosine phosphoprotein p62 Src-associated in mitosis 68 kDa protein |
| Locus: |
1p35, 2 |
| Discovery year: |
2002-02-28 |
| GenBank acession: |
U78971 |
| Entrez gene record: |
10657 |
| Pubmed identfication: |
1374686 10564820 |
| RefSeq identity: |
NM_006559 |
| Classification: |
Signal transduction and activation of RNA metabolism family |
| Havana BLAST/BLAT: |
OTTHUMG00000003921 |