| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
AIF1 |
| Specificity: |
This antibody reacts specifically with AIF1 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Subcellular locations: |
Membrane bound, Cytoplasm |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human AIF1 |
| Gene ID: |
199 |
| Swiss Prot: |
P55008 |
| Applications: |
IF(IHC-F), IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-F)(1:50-200), IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Binds calcium, Enhances lymphocyte migration, Enhances the actin-bundling activity of LCP1, May play a role in macrophage activation and function, Plays a role in RAC signaling and in phagocytosis, Plays a role in vascular inflammation, Promotes the proliferation of vascular smooth muscle cells and of T-lymphocytes, Actin-binding protein that enhances membrane ruffling and RAC activation |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
IRT-1 AIF-1 Em:AF129756, 17 IBA1 |
| Also known as: |
AIF1 Polyclonal Antibody |
| Other name: |
Anti-AIF1 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
AIF1 |
| Short name: |
Anti-AIF1 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-allograft inflammatory factor 1 (polyclonal) |
| Alternative technique: |
polyclonals |
| Alternative to gene target: |
AIF-1 and IBA1 and IRT-1 and IRT1, AIF1 and IDBG-634144 and ENSBTAG00000020554 and 280989, AIF1 and IDBG-78190 and ENSG00000204472 and 199, Aif1 and IDBG-177226 and ENSMUSG00000024397 and 11629, actin filament binding, engulfment and biological process this GO :0006954 and inflammatory response and biological process this GO :0010629 and negative regulation of gene expression and biological process this GO :0014739 and positive regulation of muscle hyperplasia and biological process this GO :0016601 and Rac protein signal transduction and biological process this GO :0030027 and lamellipodium and cellular component this GO :0030041 and actin filament polymerization and biological process this GO :0030335 and positive regulation of cell migration and biological process this GO :0031668 and cellular response to extracellular stimulus and biological process this GO :0032587 and ruffle membrane and cellular component this GO :0032870 and cellular response to hormone stimulus and biological process this GO :0034097 and response to cytokine and biological process this GO :0042102 and positive regulation of T cell proliferation and biological process this GO :0042995 and cell projection and cellular component this GO :0043066 and negative regulation of apoptotic process and biological process this GO :0043204 and perikaryon and cellular component this GO :0045429 and positive regulation of nitric oxide biosynthetic process and biological process this GO :0048471 and perinuclear region of cytoplasm and cellular component this GO :0048661 and positive regulation of smooth muscle cell proliferation and biological process this GO :0048662 and negative regulation of smooth muscle cell proliferation and biological process this GO :0048678 and response to axon injury and biological process this GO :0051015 and actin filament binding and molecular function this GO :0051017 and actin filament bundle assembly and biological process this GO :0051602 and response to electrical stimulus and biological process this GO :0071315 and cellular response to morphine and biological process this GO :0071346 and cellular response to interferon-gamma and biological process this GO :0071447 and cellular response to hydroperoxide and biological process this GO :0071672 and negative regulation of smooth muscle cell chemotaxis and biological process this GO :0071673 and positive regulation of smooth muscle cell chemotaxis and biological process this GO :0090026 and positive regulation of monocyte chemotaxis and biological process this GO :0097178 and ruffle assembly and biological process this GO :1900087 and positive regulation of G1/S transition of mitotic cell cycle and biological process this GO :2000406 and positive regulation of T cell migration and biological process, nuclei, this GO :0001726 and ruffle and cellular component this GO :0001774 and microglial cell activation and biological process this GO :0001891 and pha this GO cytic cup and cellular component this GO :0001934 and positive regulation of protein phosphorylation and biological process this GO :0003674 and molecular function and molecular function this GO :0005509 and calcium ion binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005829 and cytosol and cellular component this GO :0005884 and actin filament and cellular component this GO :0006911 and pha this GO cytosis, this GO :0003674 : molecular_function, this GO :0003674 : molecular_function and also this GO :0005509 : calcium ion binding and also this GO :0005515 : protein binding and also this GO :0051015 : actin filament binding, this GO :0005509 : calcium ion binding, this GO :0005515 : protein binding, this GO :0051015 : actin filament binding, allograft inflammatory factor 1 |
| Identity: |
352 |
| Gene: |
AIF1 |
More about : AIF1 |
| Long gene name: |
allograft inflammatory factor 1 |
| Synonyms name: |
interferon gamma responsive transcript ionized calcium-binding adapter molecule 1 |
| Locus: |
6p21, 33 |
| Discovery year: |
1997-07-01 |
| GenBank acession: |
U19713 |
| Entrez gene record: |
199 |
| Pubmed identfication: |
8912632 |
| Classification: |
EF-hand domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000031246 |