| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
AHNAK |
| Specificity: |
This antibody reacts specifically with AHNAK |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human AHNAK |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
AHNAK also appears to influence b-adrenergic regulation of cardiac L-type Ca2+ channel function, AHNAK is believed to be an important signalling molecule involved in a wide range of physiological activities and may be required for neuronal cell differentiation, Several putative regulatory elements are clustered within the C-terminal region, The central region seems to have antiparallel beta-strands connected by intervening loops, The intronless AHNAK gene is located on human chromosome 11q12 and has three main structural regions: the 251 amino acid N-terminus, a large central region of 4390 amino acids with multiple repeated units of about 128 amino acids in length, a leucine zipper, and potential phosphorylation sites for Akt1 and PKC, and the 1002 amino acid C-terminus, including nuclear export localization signals, 890 amino acid protein encoded by the human gene AHNAK, AHNAK is a 5 |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
MGC5395 |
| Also known as: |
AHNAK Polyclonal Antibody |
| Other name: |
Anti-AHNAK Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
AHNAK |
| Short name: |
Anti-AHNAK (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-AHNAK (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
347 |
| Gene: |
AHNAK |
More about : AHNAK |
| Long gene name: |
AHNAK nucleoprotein |
| Synonyms gene name: |
AHNAK nucleoprotein (desmoyokin) |
| Synonyms name: |
desmoyokin |
| Locus: |
11q12, 3 |
| Discovery year: |
1994-12-12 |
| GenBank acession: |
M80899 |
| Entrez gene record: |
79026 |
| Pubmed identfication: |
7987395 12153988 |
| RefSeq identity: |
NM_024060 |
| Classification: |
PDZ domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000167558 |