| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
GPR3 |
| Specificity: |
This antibody reacts specifically with GPR3 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Subcellular locations: |
Extracellular |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human G-protein coupled receptor 3 |
| Gene ID: |
2827 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
GPR3 is a mutli-pass membrane protein that is located on the cellular membrane of cells and is detected at low levels in the eye, GPR3 is most highly expressed in the central nervous system, In oocytes, Mice deficient for GPR3 are able to reproduce but have no control over the oocyte maturation process, The function of GPR3 is mediated by G proteins which activate adenylate cyclase, also designated ACCA orphan receptor, is a 330 amino acid member of the G protein-coupled receptor 1 family, kidney, leading to neurite outgrowth and myelin inhibition, lung, ovary and testis, this control over cAMP production can halt meiosis and prevent progesterone-induced meiotic maturation, where it stimulates the production of cAMP, which results in nondeveloping early embryos and fragmented oocytes as the mice age, G protein-coupled receptor 3 (GPR3) |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
ACCA |
| Also known as: |
GPR3 Polyclonal Antibody |
| Other name: |
Anti-GPR3 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
GPR3 |
| Short name: |
Anti-GPR3 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-GPR3 (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
4484 |
| Gene: |
GPR3 |
More about : GPR3 |
| Long gene name: |
G protein-coupled receptor 3 |
| Locus: |
1p36, 11 |
| Discovery year: |
1994-07-22 |
| GenBank acession: |
BC032702 |
| Entrez gene record: |
2827 |
| Pubmed identfication: |
7851889 |
| RefSeq identity: |
NM_005281 |
| Classification: |
Class A orphans , G protein-coupled receptors |
| Havana BLAST/BLAT: |
OTTHUMG00000003397 |