| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
GPR146 |
| Specificity: |
This antibody reacts specifically with GPR146 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Subcellular locations: |
Extracellular |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human G protein coupled receptor 146 |
| Gene ID: |
115330 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Characterized as an orphan receptor for which its endogenous ligand has yet to be identified, G protein coupled receptors translate extracellular signals into intracellular signals (G protein activation) and they respond to a variety of signaling molecules, GPR146 (G protein-coupled receptor 146), GPR146 is thought to play a role in signaling events throughout the cell, also known as PGR8, also known as seven transmembrane receptors, comprise a superfamily of proteins that play a role in many different stimulus-response pathways, heptahelical receptors or 7TM receptors, is a 333 amino acid multi-pass transmembrane protein that belongs to the G-protein coupled receptor 1 family, such as hormones and neurotransmitters, G protein-coupled receptors (GPRs) |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
PGR8 |
| Also known as: |
GPR146 Polyclonal Antibody |
| Other name: |
Anti-GPR146 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
GPR146 |
| Short name: |
Anti-GPR146 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-GPR146 (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
21718 |
| Gene: |
GPR146 |
More about : GPR146 |
| Long gene name: |
G protein-coupled receptor 146 |
| Locus: |
7p22, 3 |
| Discovery year: |
2003-07-14 |
| GenBank acession: |
BC014241 |
| Entrez gene record: |
115330 |
| RefSeq identity: |
NM_138445 |
| Classification: |
Class A orphans , G protein-coupled receptors |
| Havana BLAST/BLAT: |
OTTHUMG00000023934 |