| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
GNPDA1 |
| Specificity: |
This antibody reacts specifically with GNPDA1 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human GNPDA1 |
| Gene ID: |
10007 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
A hamster protein named oscillin is thought to be involved in this pathway, Both proteins exist as homohexamers and are ubiquitously expressed with highest expression in testis, GNPDA1 and GNPDA2 catalyze the conversion of GNP to fructose-6-phosphate and ammonia, The enzyme glucosamine-6-phosphate isomerase (GNPI) or deaminase (GNPDA1) and the related protein GNPDA2 are the human homologs of hamster oscillin, This increased calcium concentration induces a characteristic series of oscillations that trigger egg activation and early embryo development, Three isoforms of GNPDA2 are expressed due to alternative splicing events, ovary and heart, the sperm activates the egg by causing an increase in the level of free cytoplasmic calcium concentration, During fertilization in mammals |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
GNPDA HLN GPI KIAA0060 |
| Also known as: |
GNPDA1 Polyclonal Antibody |
| Other name: |
Anti-GNPDA1 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
GNPDA1 |
| Short name: |
Anti-GNPDA1 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-GNPDA1 (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
4417 |
| Gene: |
GNPDA1 |
More about : GNPDA1 |
| Long gene name: |
glucosamine-6-phosphate deaminase 1 |
| Synonyms gene: |
GNPI |
| Synonyms gene name: |
glucosamine-6-phosphate isomerase |
| Synonyms name: |
glucosamine-6-phosphate deaminase oscillin |
| Locus: |
5q31, 3 |
| Discovery year: |
1999-09-09 |
| GenBank acession: |
AF048826 |
| Entrez gene record: |
10007 |
| Pubmed identfication: |
9714720 9438414 |
| RefSeq identity: |
NM_005471 |
| Havana BLAST/BLAT: |
OTTHUMG00000129657 |