| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
GGH/Glutamyl hydrolase gamma |
| Specificity: |
This antibody reacts specifically with GGH/Glutamyl hydrolase gamma |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human GGH/Glutamyl hydrolase gamma |
| Gene ID: |
8836 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Functioning as a hydrolase, GGH contains one gamma-glutamyl hydrolase domain through which it catalyzes the hydrolysis of polyglutamate sidechains from pteroylpolyglutamates, GGH may play a role in the bioavailability and metabolic activity of pteroylpolyglutamates, Polymorphisms in the gene encoding GGH are associated with rheumatoid arthritis, The gene encoding GGH maps to human chromosome 8, Via its catalytic activity, houses more than 800 genes and is associated with a variety of diseases and malignancies, inflammatory bowel disease and various cancers, specifically hydrolyzing gamma-glutamyl bonds, which consists of nearly 146 million base pairs, GGH is a 318 amino acid protein that is secreted into the extracellular space and is also localized to both the lysosome and the melanosome |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Also known as: |
GGH/Glutamyl hydrolase gamma Antibody |
| Other name: |
Anti-GGH/Glutamyl hydrolase gamma |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Gene target: |
GGH/Glutamyl hydrolase gamma |
| Short name: |
Fluor 594, Anti-GGH/Glutamyl hydrolase gamma |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-GGH/Glutamyl hydrolase g |
| Identity: |
4248 |
| Gene: |
GGH |
More about : GGH |
| Long gene name: |
gamma-glutamyl hydrolase |
| Synonyms name: |
conjugase folylpolygammaglutamyl hydrolase |
| Locus: |
8q12, 3 |
| Discovery year: |
1999-02-10 |
| GenBank acession: |
U55206 |
| Entrez gene record: |
8836 |
| Pubmed identfication: |
8816764 10570974 |
| Havana BLAST/BLAT: |
OTTHUMG00000164365 |