| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
GluR1 Thr856 |
| Specificity: |
This antibody reacts specifically with GluR1 (Thr856) |
| Modification: |
Phosphorylation |
| Modification site: |
Thr856 |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic phosphopeptide derived from human Glutamate Receptor 1 around the phosphorylation site of Thr856 |
| Gene ID: |
2890 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Binding of the excitatory neurotransmitter L-glutamate induces a conformation change, In the presence of CACNG4 or CACNG7 or CACNG8, L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system, The receptor then desensitizes rapidly and enters a transient inactive state, and thereby converts the chemical signal to an electrical impulse, characterized by the presence of bound agonist, leading to the opening of the cation channel, shows resensitization which is characterized by a delayed accumulation of current flux upon continued application of glutamate, Ionotropic glutamate receptor |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
AMPA 1, AMPA-selective glutamate receptor 1, GLUH1, GLUR1, GRIA1, GluA1, GluR-1, GluR-A, GluR-K1, Glutamate receptor ionotropic, Glutamate receptor 1 |
| Also known as: |
GluR1 (Thr856) Polyclonal Antibody |
| Other name: |
Anti-GluR1 (Thr856) Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
GluR1 (Thr856) |
| Short name: |
Anti-GluR1 (Thr856) (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-GluR1 (Thr856) (polyclonal) |
| Alternative technique: |
polyclonals |