| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
GLUT6/Glucose Transporter GLUT6 |
| Specificity: |
This antibody reacts specifically with GLUT6/Glucose Transporter GLUT6 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human GLUT6/Glucose Transporter GLUT6 |
| Gene ID: |
11182 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Glucose binds to a Glut on one side of the membrane which provokes a conformational change causing it to release glucose to the other side, Glut6 is mainly expressed in the brain, Glut6 is part of the third out of three classes of Gluts, Gluts are integral membrane proteins that transport glucose and related hexoses, It appears to be regulated by subcellular redistribution, Members of the Glut family may enhance the metabolic activity of tumor cells, The plasma membrane is impermeable to glucose, because it is targeted to intracellular compartments by di-leucine motifs, recycling itself in a Dynamin-dependent manner, so the cellular uptake of this important nutrient is achieved by facultative hexose transproters (Gluts), spleen and peripheral leukocytes, The oxidation of glucose functions as the dominant source of metabolic energy for mammals |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
GLUT9 GLUT6 HSA011372 |
| Also known as: |
GLUT6/Glucose Transporter GLUT6 Antibody |
| Other name: |
Anti-GLUT6/Glucose Transporter GLUT6 |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Gene target: |
GLUT6/Glucose Transporter GLUT6 |
| Short name: |
Fluor 594, Anti-GLUT6/Glucose Transporter GLUT6 |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-GLUT6/Glucose Transporter GLUT6 |
| Identity: |
11011 |
| Gene: |
SLC2A6 |
More about : SLC2A6 |
| Long gene name: |
solute carrier family 2 member 6 |
| Synonyms gene name: |
member 6 , solute carrier family 2 (facilitated glucose transporter) |
| Locus: |
9q34, 2 |
| Discovery year: |
1999-09-07 |
| GenBank acession: |
AJ011372 |
| Entrez gene record: |
11182 |
| Pubmed identfication: |
10970791 |
| RefSeq identity: |
NM_017585 |
| Classification: |
Solute carriers |
| Havana BLAST/BLAT: |
OTTHUMG00000020874 |