| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
ADRM1 |
| Specificity: |
This antibody reacts specifically with ADRM1 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human ADRM1 |
| Gene ID: |
11047 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
ADRM1 expression is induced by IFN-g in some cancer cell lines and its expression is upregulated in other metastatic cells, ADRM1 functions to recruit UCH-L5, ADRM1 is thought to mediate lymphocyte adhesion in endothelial cells and may thus play a role in lymphocyte homing, Additionally, An integral membrane protein, Two isoforms of ADRM1 exist due to alternative splicing events, a deubiquitinating enzyme, and once at the proteasome it promotes the activity of UCH-L5, suggesting a role in carcinogenesis, to the 26S proteasome, ADRM1 is a 407 amino acid protein that localizes to both the nucleus and the cytoplasm and is thought to be involved in protein recruitment and cell adhesion |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
GP110 Rpn13 ARM1 |
| Also known as: |
ADRM1 Polyclonal Antibody |
| Other name: |
Anti-ADRM1 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
ADRM1 |
| Short name: |
Anti-ADRM1 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-adhesion regulating molecule 1 (polyclonal) |
| Alternative technique: |
polyclonals |
| Alternative to gene target: |
ADRM1 and IDBG-640954 and ENSBTAG00000003058 and 519729, ADRM1 and IDBG-84373 and ENSG00000130706 and 11047, ARM-1 and ARM1 and GP110, nuclei, proteasome binding, this GO :0000502 and proteasome complex and cellular component this GO :0002020 and protease binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0005887 and integral component of plasma membrane and cellular component this GO :0006368 and transcription elongation from RNA polymerase II promoter and biological process this GO :0010950 and positive regulation of endopeptidase activity and biological process this GO :0016020 and membrane and cellular component this GO :0043248 and proteasome assembly and biological process this GO :0061133 and endopeptidase activator activity and molecular function this GO :0070628 and proteasome binding and molecular function, this GO :0002020 : protease binding, this GO :0002020 : protease binding and also this GO :0005515 : protein binding and also this GO :0061133 : endopeptidase activator activity and also this GO :0070628 : proteasome binding, this GO :0005515 : protein binding, this GO :0061133 : endopeptidase activator activity, this GO :0070628 : proteasome binding, adhesion regulating molecule 1 |
| Identity: |
15759 |
| Gene: |
ADRM1 |
More about : ADRM1 |
| Long gene name: |
adhesion regulating molecule 1 |
| Locus: |
20q13, 33 |
| Discovery year: |
2001-09-17 |
| GenBank acession: |
D64154 |
| Entrez gene record: |
11047 |
| Pubmed identfication: |
8033103 |
| Havana BLAST/BLAT: |
OTTHUMG00000032904 |