| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
GGT5 heavy chain |
| Specificity: |
This antibody reacts specifically with GGT5 heavy chain |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Subcellular locations: |
Extracellular |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human Gamma-glutamyltransferase 5 heavy chain |
| Gene ID: |
2687 |
| Applications: |
IF(IHC-P), FCM |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200), FCM(1:20-100) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
GGT1 is released into the bloodstream after liver damage and an elevated level of the enzyme may be a useful early sign of hepatocellular carcinoma, GGT5 converts Leukotriene C4 to Leukotriene D4, In human serum and tissues there is a marked heterogeneity in GGT, In humans, This enzyme is located on the outer surface of the cell membrane and is widely distributed in mammalian tissues involved in absorption and secretion, but this heterogeneity can be attributed to different glycosylation of the same peptide rather than to the products of different genes, convert synthetic substrates that are commonly used to assay GGT, hepatic GGT activity is elevated in some liver diseases, however, it does not, g-glutamyltranspeptidase (GGT) acts as a glutathionase and catalyzes the transfer of the glutamyl moiety of Glutathione to a variety of amino acids and dipeptide acceptors |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
GGT-REL |
| Also known as: |
GGT5 heavy chain Polyclonal Antibody |
| Other name: |
Anti-GGT5 heavy chain Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
GGT5 heavy chain |
| Short name: |
Anti-GGT5 heavy chain (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-GGT5 heavy epitope (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
4260 |
| Gene: |
GGT5 |
More about : GGT5 |
| Long gene name: |
gamma-glutamyltransferase 5 |
| Synonyms gene: |
GGTLA1 |
| Synonyms gene name: |
gamma-glutamyltransferase-like activity 1 |
| Locus: |
22q11, 23 |
| Discovery year: |
1992-08-24 |
| GenBank acession: |
M64099 |
| Entrez gene record: |
2687 |
| Pubmed identfication: |
1676842 8095916 18357469 |
| RefSeq identity: |
NM_004121 |
| Classification: |
Gamma-glutamyltransferases |
| Havana BLAST/BLAT: |
OTTHUMG00000150796 |