| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
GBA3/CBG |
| Specificity: |
This antibody reacts specifically with GBA3/CBG |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human GBA3/CBG |
| Gene ID: |
57733 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Although its catalytic activity extends to many dietary flavonoids, CBG has increased specificity for hydrophobic aglycones such as beta-D-glucoside and beta-D-galactoside, CBG is able to hydrolyze a variety of glycosides including phytoestrogens, CBG is found predominately in the liver, Deficiencies in CBG have been implicated in Gaucherâ, Hydrolysis is inhibited by sodium taurocholate and glucosyl-sphingosine, Through its catalytic activity, a lysosomal storage disease that causes a build up of fatty material in the spleen, and flavonols, both of which regulate CBG enzymatic activity, but is also located in tissues such as spleen, cyanogens, liver, lung and kidneys, small intestine and kidney, &euro, &trade, CBG is a monomeric enzyme involved in the absorption and metabolism of flavonoid glucosides, s disease |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
GLUC KLrP |
| Also known as: |
GBA3/CBG Polyclonal Antibody |
| Other name: |
Anti-GBA3/CBG Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
GBA3/CBG |
| Short name: |
Anti-GBA3/CBG (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-GBA3/CBG (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
19069 |
| Gene: |
GBA3 |
More about : GBA3 |
| Long gene name: |
glucosylceramidase beta 3 (gene/pseudogene) |
| Synonyms gene name: |
acid 3 (cytosolic) glucosidase, acid 3 (gene/pseudogene) , beta, beta, glucosidase |
| Synonyms name: |
klotho-related protein |
| Locus: |
4p15, 2 |
| Discovery year: |
2002-12-16 |
| GenBank acession: |
AB017913 |
| Entrez gene record: |
57733 |
| Pubmed identfication: |
11389701 |
| Havana BLAST/BLAT: |
OTTHUMG00000160448 |