| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
GART |
| Specificity: |
This antibody reacts specifically with GART |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human GART |
| Gene ID: |
2618 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Cancer cells require considerable amounts of purines to sustain their accelerated growth and GART is, GARS, GART (GAR transformylase), GART is highly conserved in vertebrates, PAIS, PGFT, PRGS or GARTF, Two isoforms of GART are expressed due to alternative splicing events, a target for cancer chemotherapy, also referred to as AIRS, cell signaling and cell reproduction and also function as precursors for coenzymes, energy transfer molecules, is 1, phosphoribosylglycinamide synthetase and AICAR (phosphoribosylaminoimidazole synthetase) activity required for de novo purine biosynthesis, regulatory factors and proteins involved in RNA and DNA synthesis, therefore, 010 amino acids in length and is a key folate-dependent trifunctional enzyme with phosphoribosylglycinamide formyltransferase, Purines are critical for energy metabolism |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Also known as: |
GART Polyclonal Antibody |
| Other name: |
Anti-GART Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
GART |
| Short name: |
Anti-GART (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-GART (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
4163 |
| Gene: |
GART |
More about : GART |
| Long gene name: |
phosphoribosylaminoimidazole synthetase , phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase |
| Synonyms gene: |
PRGS PGFT |
| Locus: |
21q22, 11 |
| Discovery year: |
2001-06-22 |
| GenBank acession: |
M32082 |
| Entrez gene record: |
2618 |
| Pubmed identfication: |
2050105 |
| RefSeq identity: |
NM_000819 |
| Havana BLAST/BLAT: |
OTTHUMG00000065628 |