| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
gamma Crystallin |
| Specificity: |
This antibody reacts specifically with gamma Crystallin |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Subcellular locations: |
Nucleus, Cytoplasm |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human gamma C Crystallin/CRYG3 |
| Gene ID: |
1418, 1419, 1420, 1421, 1422 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Crystallins are divided into alpha, Crystallins usually contain seven distinctive protein regions, The gamma-crystallins are differentially regulated after early development, The gamma-crystallins include seven closely related gamma A, a connecting peptide, and N- and C-terminal extensions, and are involved in cataract formation as a result of either age-related protein degradation or genetic mutation, and gamma G-crystallin, and gamma families, and the beta and gamma-crystallins also comprise a superfamily, and they exists as monomers which typically lack connecting peptides and terminal extensions, as well as the gamma N and gamma S-crystallin genes, beta, gamma B, gamma C, gamma D, gamma E, gamma F, gamma-crystallins are structural proteins in the lens, including four homologous motifs, where they maintain the transparency and refractive index of the lens, Crystallins are the major proteins of the vertebrate eye lens |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
CRYG5 CRY-g-A |
| Also known as: |
gamma Crystallin Polyclonal Antibody |
| Other name: |
Anti-gamma Crystallin Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
gamma Crystallin |
| Short name: |
Anti-gamma Crystallin (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-g Crystallin (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
2408 |
| Gene: |
CRYGA |
More about : CRYGA |
| Long gene name: |
crystallin gamma A |
| Synonyms gene: |
CRYG1 |
| Synonyms gene name: |
crystallin, gamma A |
| Synonyms name: |
gamma crystallin 5 |
| Locus: |
2q33, 3 |
| Discovery year: |
1986-01-01 |
| Entrez gene record: |
1418 |
| RefSeq identity: |
NM_014617 |
| Classification: |
Beta-gamma crystallins |
| Havana BLAST/BLAT: |
OTTHUMG00000154796 |