| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
GALE/Galactowaldenase |
| Specificity: |
This antibody reacts specifically with GALE/Galactowaldenase |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human GALE/Galactowaldenase |
| Gene ID: |
2582 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
A member of the sugar epimerase family, GALE exists as a homodimer, The gene encoding GALE maps to human chromosome 1p36, binds FAD as a cofactor and catalyzes the epimerization of UDP-N-acetylglucosamine to UDP-N-acetylgalactosamine and UDP-glucose to UDP-galactose, cataracts and deafness, liver damage, which is characterized by mental retardation, 11 and mutations in this gene lead to the development of complex disorder known as epimerase-deficiency galactosemia (EDG) or galactosemia type 3, GALE is a 348 amino acid protein that functions as the third enzyme in the Leloir pathway of galactose metabolism |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
SDR1E1 |
| Also known as: |
GALE/Galactowaldenase Antibody |
| Other name: |
Anti-GALE/Galactowaldenase |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Gene target: |
GALE/Galactowaldenase |
| Short name: |
Fluor 594, Anti-GALE/Galactowaldenase |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-GALE/Galactowaldenase |
| Identity: |
4116 |
| Gene: |
GALE |
More about : GALE |
| Long gene name: |
UDP-galactose-4-epimerase |
| Synonyms gene name: |
UDP- , galactose-4-epimerase |
| Synonyms name: |
member 1 UDP-glucose 4-epimerase , short chain dehydrogenase/reductase family 1E |
| Locus: |
1p36, 11 |
| Discovery year: |
2001-06-22 |
| GenBank acession: |
BC050685 |
| Entrez gene record: |
2582 |
| Pubmed identfication: |
8593531 19027726 |
| RefSeq identity: |
NM_000403 |
| Classification: |
Short chain dehydrogenase/reductase superfamily |
| Havana BLAST/BLAT: |
OTTHUMG00000002958 |