| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
GNA11 |
| Specificity: |
This antibody reacts specifically with GNA11 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human GNA11 |
| Gene ID: |
2767 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
4 and 7 genes, Each of a very broad range of receptors specifically detects an extracellular stimulus (a photon, Four distinct classes of Ga subunits have been identified, G alpha 11 and G alpha q, G alpha 11 and G alphaq, G alpha 14, G protein alpha, Gi, Gq and Ga 12/13 (3, In mammals, Most interest in G proteins has been focused on their alpha subunits, The Gq class includes G alpha 15, adenyl cyclase), are abundant in brain and lung and present at lower levels in a variety of tissues (6), are less numerous, beta and gamma polypeptides are encoded by at least 16, hormone or neurotransmitter) while the effectors (e, odorant, pheromone, respectively (2-5), since these proteins bind and hydrolyze GTP and most obviously regulate the activity of the best studied effectors, these include Gs, two of which, which act to generate one or more intracellular messengers, 4), Heterotrimeric G proteins function to relay information from cell surface receptors to intracellular effectors (1), g |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
FBH FBH2 FHH2 |
| Also known as: |
GNA11 Polyclonal Antibody |
| Other name: |
Anti-GNA11 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
GNA11 |
| Short name: |
Anti-GNA11 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-GNA11 (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
4379 |
| Gene: |
GNA11 |
More about : GNA11 |
| Long gene name: |
G protein subunit alpha 11 |
| Synonyms gene: |
HHC2 |
| Synonyms gene name: |
alpha 11 (Gq class) , hypocalciuric hypercalcemia 2 guanine nucleotide binding protein (G protein) |
| Locus: |
19p13, 3 |
| Discovery year: |
1992-07-20 |
| GenBank acession: |
AF493900 |
| Entrez gene record: |
2767 |
| Pubmed identfication: |
1302014 23802516 |
| RefSeq identity: |
NM_002067 |
| Havana BLAST/BLAT: |
OTTHUMG00000180631 |
| Locus Specific Databases: |
LRG_1111 |