| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
FLNC 2233 |
| Specificity: |
This antibody reacts specifically with FLNC (Ser2233) |
| Modification: |
Phosphorylation |
| Modification site: |
Ser2233 |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic phosphopeptide derived from human FLNC around the phosphorylation site of Ser2233 |
| Gene ID: |
2318 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Filamin 2, Filamin 2 and Filamin 3, Filamins also participate in signal transduction pathways associated with cell motility, Filamins help reshape the cytoskeleton by forming flexible cross-links between two Actin filaments, Muscular dystrophy, The filamin family is comprised of Filamin 1, a membrane glycoprotein domain and a C-terminal self-association domain, a protein that interacts with Filamin 2, adhesion, also designated Filamin C, an inherited group of disorders resulting in progressive weakness of muscles in the body, and force transduction, but not &, differentiation and survival, is a skeletal- and cardiac-muscle specific form of Filamin, is associated with irregular subcellular localization of Filamin 2 caused by a deficiency in KY, which binds &, which maintain membrane integrity during force application, #8706, &circ, «, -sarcoglycan, -sarcoglycan, -sarcoglycan and &, -sarcoglycan or â, Filamins are Actin-binding proteins which contain an N-terminal Actin-binding domain, aring, copy |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
ABP-280 ABPL |
| Also known as: |
FLNC (Ser2233) Polyclonal Antibody |
| Other name: |
Anti-FLNC (Ser2233) Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
FLNC (Ser2233) |
| Short name: |
Anti-FLNC (Ser2233) (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-FLNC (Ser2233) (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
3756 |
| Gene: |
FLNC |
More about : FLNC |
| Long gene name: |
filamin C |
| Synonyms gene: |
FLN2 |
| Synonyms gene name: |
filamin C, gamma , gamma (actin binding protein 280) filamin C |
| Synonyms name: |
actin binding protein 280 gamma filamin |
| Locus: |
7q32, 1 |
| Discovery year: |
1993-08-24 |
| GenBank acession: |
AB208865 |
| Entrez gene record: |
2318 |
| Pubmed identfication: |
7689010 8088838 |
| Havana BLAST/BLAT: |
OTTHUMG00000023627 |
| Locus Specific Databases: |
LRG_870 |