| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
ELK4/SAP-1a |
| Specificity: |
This antibody reacts specifically with ELK4/SAP-1a |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human ELK4/SAP-1a |
| Gene ID: |
2005 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
At the c-Fos SRE, Elk-1 and SAP-1 contain two homologous regions of which the two amino terminal regions, Elk-1 and SRF accessory protein-1 (SAP-1), SRF-binding sites are also constitutive promoter elements in many muscle-specific promoters, The third homologous region, Two related Ets domain proteins, a sequence that mediates the transient response of many cellular genes to growth stimulation, contains conserved consensus phosphorylation sites for MAP kinases, formation of a ternary complex containing SRF and its accessory protein p62TCF appears to be important for signal transduction, have DNA binding properties identical to that of p62TCF, mediate ternary complex formation with SRF, the C box located toward the C-terminus of the proteins, the Ets domain (box A) and the B box, Serum response factor (SRF) is a transcription factor that binds the serum response element (SRE) |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
SAP1 |
| Also known as: |
ELK4/SAP-1a Polyclonal Antibody |
| Other name: |
Anti-ELK4/SAP-1a Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
ELK4/SAP-1a |
| Short name: |
Anti-ELK4/SAP-1a (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-ELK4/SAP-1a (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
3326 |
| Gene: |
ELK4 |
More about : ELK4 |
| Long gene name: |
ELK4, ETS transcription factor |
| Synonyms gene name: |
ELK4, ETS-domain protein (SRF accessory protein 1) |
| Synonyms name: |
SRF accessory protein 1 |
| Locus: |
1q32, 1 |
| Discovery year: |
1994-12-23 |
| GenBank acession: |
M85165 |
| Entrez gene record: |
2005 |
| Pubmed identfication: |
7851904 8575773 |
| RefSeq identity: |
NM_021795 |
| Classification: |
ETS transcription factor family |
| Havana BLAST/BLAT: |
OTTHUMG00000037221 |