| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
Dymeclin |
| Specificity: |
This antibody reacts specifically with Dymeclin |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human Dymeclin |
| Gene ID: |
54808 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Cutaneous cells of affected individuals show dilated rough endoplasmic reticulum and enlarged vacuoles, Defects in dymeclin are also the cause of Smith-McCort dysplasis syndrome (SMC), It is a widely expressed multi-pass membrane protein, The Dyggve-Melchior-Clausen syndrome protein, a rare autosomal recessive disorder, also designated dymeclin, detected primarily in chondrocytes and fetal brain tissue, is characterized by microcephaly, may play a role in proteoglycan metabolism and intracellular protein digestion, short trunk dwarfism and sometime psychomotor retardation, which has characteristics identical to those of Dyggve-Melchior-Clausen syndrome, Dyggve-Melchior-Clausen syndrome (DMC) |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
FLJ20071 DMC SMC |
| Also known as: |
Dymeclin Polyclonal Antibody |
| Other name: |
Anti-Dymeclin Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
Dymeclin |
| Short name: |
Anti-Dymeclin (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-Dymeclin (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
21317 |
| Gene: |
DYM |
More about : DYM |
| Long gene name: |
dymeclin |
| Locus: |
18q21, 1 |
| Discovery year: |
2005-01-05 |
| GenBank acession: |
AK000078 |
| Entrez gene record: |
54808 |
| RefSeq identity: |
NM_017653 |
| Havana BLAST/BLAT: |
OTTHUMG00000132659 |