| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
DNA polymerase mu |
| Specificity: |
This antibody reacts specifically with DNA polymerase mu |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human DNA polymerase mu |
| Gene ID: |
27434 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
DNA Pol mu incorporates both deoxynucleotides and ribonucleotides in a template- directed manner, However, Pol mu purportedly plays a role in microhomology mediated joining and the repair of double-stranded breaks, This unusual capability implies a novel role for this polymerase in DNA repair, unlike other DNA polymerases, which show substrate specificity for deoxynucleotides, DNA polymerase mu shares a number of characteristics with DNA polymerase Beta as well as with terminal deoxynucleotideyltransferase |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
Tdt-N |
| Also known as: |
DNA polymerase mu Polyclonal Antibody |
| Other name: |
Anti-DNA polymerase mu Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
DNA polymerase mu |
| Short name: |
Anti-DNA polymerase mu (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-Desoxyribonucleic acid polymerizing enzyme mu (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
9185 |
| Gene: |
POLM |
More about : POLM |
| Long gene name: |
DNA polymerase mu |
| Synonyms gene name: |
mu polymerase (DNA) mu , polymerase (DNA directed) |
| Synonyms name: |
Pol iota |
| Locus: |
7p13 |
| Discovery year: |
2000-02-16 |
| GenBank acession: |
AF176097 |
| Entrez gene record: |
27434 |
| Pubmed identfication: |
10982892 |
| RefSeq identity: |
NM_013284 |
| Classification: |
DNA polymerases |
| Havana BLAST/BLAT: |
OTTHUMG00000155353 |