| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
DNA Polymerase Kappa/POLK |
| Specificity: |
This antibody reacts specifically with DNA Polymerase Kappa/POLK |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human DNA Polymerase Kappa/POLK |
| Gene ID: |
51426 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Encoded by the POLL gene, In addition, Pol Kappa extends primer-terminal mispairs opposite nondamaged DNA templates, Proliferating cell nuclear antigen (PCNA), a protein essential to DNA replication, also designated DNA polymerase Kappa or Pol Beta2, interacts with pol Kappa and thus influences the ability of pol Kappa to synthesize DNA, is a low-fidelity polymerase which plays a role in both spontaneous and DNA damage-induced mutagenesis, pol Kappa is a member of the DNA polymerase type-X family, pol Kappa may play a role in the mutagenic bypass of T-T dimers, suggesting that it may assist in extending mismatched base pairs during normal DNA replication, DNA polymerase lambda (pol Kappa) |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
POLQ DINP |
| Also known as: |
DNA Polymerase Kappa/POLK Antibody |
| Other name: |
Anti-DNA Polymerase Kappa/POLK |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Gene target: |
DNA Polymerase Kappa/POLK |
| Short name: |
Fluor 594, Anti-DNA Polymerase Kappa/POLK |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-Desoxyribonucleic acid polymerizing enzyme Kappa/POLK |
| Identity: |
9183 |
| Gene: |
POLK |
More about : POLK |
| Long gene name: |
DNA polymerase kappa |
| Synonyms gene: |
DINB1 |
| Synonyms gene name: |
polymerase (DNA directed) kappa polymerase (DNA) kappa |
| Synonyms name: |
DINB protein DNA polymerase kappa |
| Locus: |
5q13, 3 |
| Discovery year: |
2000-08-11 |
| GenBank acession: |
AB027564 |
| Entrez gene record: |
51426 |
| Pubmed identfication: |
10887153 10518552 |
| RefSeq identity: |
NM_016218 |
| Classification: |
DNA polymerases |
| Havana BLAST/BLAT: |
OTTHUMG00000102107 |