| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
DIAPH2/Dia2 |
| Specificity: |
This antibody reacts specifically with DIAPH2/Dia2 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Subcellular locations: |
Cytoplasm |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human DIAPH2/Dia2 |
| Gene ID: |
1730 |
| Swiss Prot: |
O60879 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Implicated in a novel signal transduction pathway, Involved in the regulation of endosome dynamics, in which isoform 3 and CSK are sequentially activated by RHOD to regulate the motility of early endosomes through interactions with the actin cytoskeleton, Could be involved in oogenesis |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
POF DIA POF2 DIA2 |
| Also known as: |
DIAPH2/Dia2 Polyclonal Antibody |
| Other name: |
Anti-DIAPH2/Dia2 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
DIAPH2/Dia2 |
| Short name: |
Anti-DIAPH2/Dia2 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-diaphanous homolog 2 (Drosophila)/Dia2 (polyclonal) |
| Alternative technique: |
polyclonals |
| Alternative to gene target: |
Cytoplasm, DIA and DIA2 and DRF2 and POF and POF2, DIAPH2 and IDBG-78961 and ENSG00000147202 and 1730, Diap2 and IDBG-170053 and ENSMUSG00000034480 and 54004, Rho GTPase binding, this GO :0000910 and cytokinesis and biological process this GO :0003779 and actin binding and molecular function this GO :0005102 and receptor binding and molecular function this GO :0005488 and binding and molecular function this GO :0005769 and early endosome and cellular component this GO :0005829 and cytosol and cellular component this GO :0007015 and actin filament organization and biological process this GO :0007275 and multicellular organismal development and biological process this GO :0007292 and female gamete generation and biological process this GO :0016043 and cellular component organization and biological process this GO :0017048 and Rho GTPase binding and molecular function this GO :0030036 and actin cytoskeleton organization and biological process this GO :0030041 and actin filament polymerization and biological process this GO :0048477 and oogenesis and biological process, this GO :0003779 : actin binding, this GO :0003779 : actin binding and also this GO :0005102 : receptor binding and also this GO :0005488 : binding and also this GO :0017048 : Rho GTPase binding, this GO :0005102 : receptor binding, this GO :0005488 : binding, this GO :0017048 : Rho GTPase binding, diaphanous homolog 2 (Drosophila) |
| Identity: |
2877 |
| Gene: |
DIAPH2 |
More about : DIAPH2 |
| Long gene name: |
diaphanous related formin 2 |
| Synonyms gene name: |
diaphanous (Drosophila, homolog) 2 diaphanous homolog 2 (Drosophila) |
| Locus: |
Xq21, 33 |
| Discovery year: |
1998-03-17 |
| GenBank acession: |
Y15909 |
| Entrez gene record: |
1730 |
| Pubmed identfication: |
9360932 |
| RefSeq identity: |
NM_006729 NM_007309 |
| Havana BLAST/BLAT: |
OTTHUMG00000022689 |
| Locus Specific Databases: |
Mental Retardation database |