| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
Dermcidin/DCD |
| Specificity: |
This antibody reacts specifically with Dermcidin/DCD |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human Dermcidin/DCD |
| Gene ID: |
117159 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
DCD-1 displays antimicrobial activity in response to a variety of pathogenic microorganisms, Overexpression of Dermcidin in breast cancers promotes cell growth and survival, The Dermcidin gene encodes an antimicrobial peptide DCD-1, and is coupled with a focal copy number gain of its locus on human chromosome 12q13, and transported to the epidermal surface, secreted into the sweat, which is constitutively expressed in sweat glands, which may provide a barrier for protection against infection, 2, Antimicrobial peptides participate in the innate response |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
AIDD PIF DSEP HCAP DCD-1 |
| Also known as: |
Dermcidin/DCD Polyclonal Antibody |
| Other name: |
Anti-Dermcidin/DCD Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
Dermcidin/DCD |
| Short name: |
Anti-Dermcidin/DCD (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-Dermcidin/DCD (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
14669 |
| Gene: |
DCD |
More about : DCD |
| Long gene name: |
dermcidin |
| Synonyms name: |
proteolysis inducing factor preproteolysin diffusible survival/evasion peptide survival promoting peptide |
| Locus: |
12q13, 2 |
| Discovery year: |
2001-02-27 |
| GenBank acession: |
AF144011 |
| Entrez gene record: |
117159 |
| Pubmed identfication: |
11694882 |
| RefSeq identity: |
NM_053283 |
| Havana BLAST/BLAT: |
OTTHUMG00000169937 |