| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
Acetyl Coenzyme A Carboxylase alpha Ser1263 |
| Specificity: |
This antibody reacts specifically with Acetyl Coenzyme A Carboxylase alpha (Ser1263) |
| Modification: |
Phosphorylation |
| Modification site: |
Ser1263 |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic phosphopeptide derived from human Acetyl Coenzyme A Carboxylase alpha around the phosphorylation site of Ser1263 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
ACC is a biotin-containing enzyme which catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, ACC-alpha is highly enriched in lipogenic tissues, Jul 2008], Multiple alternatively spliced transcript variants divergent in the 5' sequence and encoding distinct isoforms have been found for this gene, The enzyme is under long term control at the transcriptional and translational levels and under short term regulation by the phosphorylation/dephosphorylation of targeted serine residues and by allosteric transformation by citrate or palmitoyl-CoA, There are two ACC forms, [provided by RefSeq, alpha and beta, encoded by two different genes, the rate-limiting step in fatty acid synthesis, Acetyl-CoA carboxylase (ACC) is a complex multifunctional enzyme system |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
ACAC, ACACA, ACACA, ACACA_HUMAN, ACC, ACC alpha, ACC-alpha, ACC1, ACC1, ACCA, Acetyl Coenzyme A, Acetyl-Coenzyme A Carboxylase alpha, Biotin carboxylase, acetyl CoA carboxylase 1, acetyl Coenzyme A, p-Acetyl Coenzyme A Carboxylase alpha phospho S1263, Acetyl Coenzyme A Carboxylase alpha phospho S1263 |
| Also known as: |
Acetyl Coenzyme A Carboxylase alpha (Ser1263) Antibody |
| Other name: |
Anti-Acetyl Coenzyme A Carboxylase alpha (Ser1263) |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Description: |
N terminal acetylation or CH3CO as epigenetic regulation of Anti- Coenzyme A Carboxylase alpha (Ser1263) Fluor 594 by NATs |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Gene target: |
Coenzyme A Carboxylase alpha (Ser1263) |
| Short name: |
Anti- Coenzyme A Carboxylase alpha (Ser1263) Fluor 594 |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-Acetyl Coenzyme A Carboxylase a (Ser1263) |