| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
Cytokeratin 8 Ser74 |
| Specificity: |
This antibody reacts specifically with Cytokeratin 8 (Ser74) |
| Modification: |
Phosphorylation |
| Modification site: |
Ser74 |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic phosphopeptide derived from human CK8 around the phosphorylation site of Ser74 |
| Gene ID: |
3856 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Alternatively spliced transcript variants have been found for this gene, Jan 2012], Mutations in this gene cause cryptogenic cirrhosis, The product of this gene typically dimerizes with keratin 18 to form an intermediate filament in simple single-layered epithelial cells, This protein plays a role in maintaining cellular structural integrity and also functions in signal transduction and cellular differentiation, Type I and type II keratins heteropolymerize to form intermediate-sized filaments in the cytoplasm of epithelial cells, [provided by RefSeq, This gene is a member of the type II keratin family clustered on the long arm of chromosome 12 |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
CK 8, CK-8, CYK8, CYKER, Cardiac autoantigen 2 120kD, Cyk 8, Cytokeratin 8, Cytokeratin endo A, Cytokeratin-8, Cytokeratin8, DreK8, EndoA, K2C8_HUMAN, KO, KRT-8, Keratin, Keratin 8, Keratin type ii cytoskeletal 8, Keratin-8, Keratin8, Krt 2, Krt 8, MGC118110, MGC174782, MGC53564, MGC85764, Type-II keratin Kb8, card2, ck8, cyk8, k0, k2c8, k8, krt8, p-Cytokeratin 8 phospho S74, sb:cb186, type II cytoskeletal 8, 8, Cytokeratin 8 phospho S74 |
| Also known as: |
Cytokeratin 8 (Ser74) Antibody |
| Other name: |
Anti-Cytokeratin 8 (Ser74) |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Gene target: |
Cytokeratin 8 (Ser74) |
| Short name: |
Anti-Cytokeratin 8 (Ser74) Fluor 594 |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-Cytokeratin 8 (Ser74) |