| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
beta Catenin Ser37 |
| Specificity: |
This antibody reacts specifically with beta Catenin (Ser37) |
| Modification: |
Phosphorylation |
| Modification site: |
Ser37 |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic phosphopeptide derived from human beta Catenin around the phosphorylation site of Ser37 |
| Gene ID: |
1499 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
AJs are necessary for the creation and maintenance of epithelial cell layers by regulating cell growth and adhesion between cells, Finally, Mutations in this gene are a cause of colorectal cancer (CRC), Oct 2009], The encoded protein also anchors the actin cytoskeleton and may be responsible for transmitting the contact inhibition signal that causes cells to stop dividing once the epithelial sheet is complete, Three transcript variants encoding the same protein have been found for this gene, and ovarian cancer, medulloblastoma (MDB), pilomatrixoma (PTR), this protein binds to the product of the APC gene, which is mutated in adenomatous polyposis of the colon, The protein encoded by this gene is part of a complex of proteins that constitute adherens junctions (AJs), [provided by RefSeq |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
88kDa, CATNB, CHBCAT, CTNB1_HUMAN, CTNNB, CTNNB, CTNNB1, CTNNB1, CTNNB1, Cadherin associated protein, Catenin beta 1, Catenin beta-1, Catenin cadherin associated protein, DKFZp686D02253, FLJ25606, FLJ37923, OTTHUMP00000162082, OTTHUMP00000165222, OTTHUMP00000165223, OTTHUMP00000209288, OTTHUMP00000209289, PRO2286, b-catenin, beta 1, beta Catenin phospho Ser37, beta catenin, beta-catenin, p-beta Catenin S37, p-beta Catenin Ser37, p-beta Catenin phospho S37, beta Catenin phospho S37 |
| Also known as: |
beta Catenin (Ser37) Polyclonal Antibody |
| Other name: |
Anti-beta Catenin (Ser37) Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
beta Catenin (Ser37) |
| Short name: |
Anti-beta Catenin (Ser37) (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-b Catenin (Ser37) (polyclonal) |
| Alternative technique: |
polyclonals |