| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
Band3 Tyr21 |
| Specificity: |
This antibody reacts specifically with Band3 (Tyr21) |
| Modification: |
Phosphorylation |
| Modification site: |
Tyr21 |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic phosphopeptide derived from human Band3 around the phosphorylation site of Tyr21 |
| Gene ID: |
6521 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
An isoform of band 3, Degradation of band 3 can generate an aging antigen known as senescent cell antigen, The amino terminal domain, The carboxy-terminal, The diverse functions of the approximately 900 amino acid protein are mediated by two distinct domains, acts as an attachment site for the erythrocyte skeleton by binding ankyrin, also designated AE1, also known as cdb3 for cytoplasmic domain of erthrocyte membrane band 3, is an erythrocyte membrane glycoprotein that contributes to cell stuctural integrity and mediates exchange of chloride and bicarbonate across the phospholipid bilayer, is expressed in kidney, membrane-associated domain carries out exchange transport of anions, or SCA, which is expressed on old cells and marks them for removal by the immune system, which lacks the first 65 amino acids and does not bind ankryin, Band 3 |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
AE 1, AE1, Anion exchange protein 1, Anion exchanger 1, B3AT_HUMAN, BND3, Band 3, Band 3 anion transport protein, CD233, DI, Diego blood group, EMPB3, EPB3, Erythrocyte membrane protein band 3, Erythroid anion exchange protein, FR antibod, Froese blood group, RTA1A, SLC4A1, SW antibody, Solute carrier family 4 anion exchanger member 1, Solute carrier family 4 member 1, Solute carrier family 4 member 1, Swann blood group, WD antibody, WD1, WR antibody, Waldner blood group, Wright blood group, p-Band 3 phospho Y21, Band 3 phospho Y21 |
| Also known as: |
Band3 (Tyr21) Polyclonal Antibody |
| Other name: |
Anti-Band3 (Tyr21) Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
Band3 (Tyr21) |
| Short name: |
Anti-Band3 (Tyr21) (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-Band3 (Tyr21) (polyclonal) |
| Alternative technique: |
polyclonals |