| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
ATF5 |
| Specificity: |
This antibody reacts specifically with ATF5 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human ATF5 |
| Gene ID: |
22809 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
ATF-1, ATF-2, ATF-3, ATF-5, ATF-5 (ATFx), ATF-6 and ATF-7, CRE-BPa, CREB-2 (also designated ATF-4), CREM-1, CREM-2, It interacts with CCND3 and PTP4A1, LZIP (also designated CREB3 and Luman), The ATF/CREB transcription factor family binds the palindromic cAMP response element (CRE) octanucleotide TGACGTCA, The best characterized members of this gene family include CREB-1, This family of proteins contain highly divergent N-terminal domains, binds DNA as a dimer, but share a C-terminal leucine zipper for dimerization and DNA binding, which can localize to the cytoplasm or the nucleus, Eukaryotic gene transcription is regulated by sequence-specific transcription factors that bind modular cis acting promoter and enhancer elements |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Also known as: |
ATF5 Polyclonal Antibody |
| Other name: |
Anti-ATF5 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
ATF5 |
| Short name: |
Anti-ATF5 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-activating transcription factor 5 (polyclonal) |
| Alternative technique: |
polyclonals |
| Alternative to gene target: |
ATF5 and IDBG-63891 and ENSG00000169136 and 22809, ATF5 and IDBG-640902 and ENSBTAG00000003457 and 515654, ATFX and HMFN0395, Atf5 and IDBG-179716 and ENSMUSG00000038539 and 107503, DNA-templated and biological process this GO :0006355 and regulation of transcription, DNA-templated and biological process this GO :0006357 and regulation of transcription from RNA polymerase II promoter and biological process this GO :0009791 and post-embryonic development and biological process this GO :0010468 and regulation of gene expression and biological process this GO :0021889 and olfactory bulb interneuron differentiation and biological process this GO :0021891 and olfactory bulb interneuron development and biological process this GO :0021988 and olfactory lobe development and biological process this GO :0031072 and heat shock protein binding and molecular function this GO :0035264 and multicellular organism growth and biological process this GO :0043066 and negative regulation of apoptotic process and biological process this GO :0043565 and sequence-specific DNA binding and molecular function this GO :0045944 and positive regulation of transcription from RNA polymerase II promoter and biological process this GO :0048712 and negative regulation of astrocyte differentiation and biological process this GO :0050768 and negative regulation of neurogenesis and biological process, nuclei, sequence-specific DNA binding, this GO :0000977 and RNA polymerase II regulatory region sequence-specific DNA binding and molecular function this GO :0001228 and RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription and molecular function this GO :0003700 and sequence-specific DNA binding transcription factor activity and molecular function this GO :0003714 and transcription corepressor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005667 and transcription factor complex and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0006351 and transcription, this GO :0000977 : RNA polymerase II regulatory region sequence-specific DNA binding, this GO :0000977 : RNA polymerase II regulatory region sequence-specific DNA binding and also this GO :0001228 : RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription and also this GO :0003700 : sequence-specific DNA binding transcription factor activity and also this GO :0003714 : transcription corepressor activity and also this GO :0005515 : protein binding and also this GO :0031072 : heat shock protein binding and also this GO :0043565 : sequence-specific DNA binding, this GO :0001228 : RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription, this GO :0003700 : sequence-specific DNA binding transcription factor activity, this GO :0003714 : transcription corepressor activity, this GO :0005515 : protein binding, this GO :0031072 : heat shock protein binding, this GO :0043565 : sequence-specific DNA binding, activating transcription factor 5 |
| Identity: |
790 |
| Gene: |
ATF5 |
More about : ATF5 |
| Long gene name: |
activating transcription factor 5 |
| Locus: |
19q13, 33 |
| Discovery year: |
2000-03-22 |
| GenBank acession: |
AF101388 |
| Entrez gene record: |
22809 |
| Pubmed identfication: |
10373550 |
| Classification: |
Basic leucine zipper proteins |
| Havana BLAST/BLAT: |
OTTHUMG00000183065 |