| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
ARVCF |
| Specificity: |
This antibody reacts specifically with ARVCF |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human ARVCF |
| Gene ID: |
421 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
ARVCF contains a predicted nuclear-targeting sequence suggesting that it may have a function as a nuclear protein, In addition, Jun 2010], Since these sequences can facilitate protein-protein interactions ARVCF is thought to function in a protein complex, The ARVCF gene encodes a protein containing two motifs, The ARVCF gene was isolated in the search for the genetic defect responsible for the autosomal dominant Velo-Cardio-Facial syndrome (VCFS), This family plays an important role in the formation of adherens junction complexes, [provided by RefSeq, a coiled coil domain in the N-terminus and a 10 armadillo repeat sequence in the midregion, a relatively common human disorder with phenotypic features including cleft palate, conotruncal heart defects and facial dysmorphology, which are thought to facilitate communication between the inside and outside environments of a cell, Armadillo Repeat gene deleted in Velo-Cardio-Facial syndrome (ARVCF) is a member of the catenin family |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Also known as: |
ARVCF Polyclonal Antibody |
| Other name: |
Anti-ARVCF Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
ARVCF |
| Short name: |
Anti-ARVCF (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-armadillo repeat gene deleted in velocardiofacial syndrome (polyclonal) |
| Alternative technique: |
polyclonals |
| Alternative to gene target: |
ARVCF and IDBG-1524 and ENSG00000099889 and 421, ARVCF and IDBG-638161 and ENSBTAG00000001473 and 517045, Arvcf and IDBG-141624 and ENSMUSG00000000325 and 11877, nuclei, protein binding, this GO :0005488 and binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005622 and intracellular and cellular component this GO :0005634 and nucleus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0007155 and cell adhesion and biological process this GO :0007275 and multicellular organismal development and biological process this GO :0016337 and single organismal cell-cell adhesion and biological process this GO :0016339 and calcium-dependent cell-cell adhesion and biological process, this GO :0005488 : binding, this GO :0005488 : binding and also this GO :0005515 : protein binding, this GO :0005515 : protein binding, armadillo repeat gene deleted in velocardiofacial syndrome |
| Identity: |
728 |
| Gene: |
ARVCF |
More about : ARVCF |
| Long gene name: |
armadillo repeat gene deleted in velocardiofacial syndrome |
| Locus: |
22q11, 21 |
| Discovery year: |
1996-10-11 |
| Entrez gene record: |
421 |
| Pubmed identfication: |
9126485 15456900 |
| RefSeq identity: |
NM_001670 |
| Classification: |
Armadillo repeat containing |
| Havana BLAST/BLAT: |
OTTHUMG00000030426 |