| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
ARL4 |
| Specificity: |
This antibody reacts specifically with ARL4 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human ARL4 |
| Gene ID: |
10124 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
ARFæ, ARL4 (ADP-ribosylation factor-like protein 4A) is a member of the ARF-like protein (ARL) subfamily of small GTPases, ARL4 does not activate the cholera toxin ADP-ribosyltranferase, ARL4 may play a role in neurogenesis during embryonic development and somitogenesis in the early stages of adult spermatogenesis, It contains a C terminal nuclear localization signal (NLS) region that interacts with Importin-? ARL4 localizes to the nucleus and is found in a variety of tissues, It is most closely related to ARL6 and ARL7, Unlike ARFs, are important in eukaryotic vesicular trafficking pathways and activating phospholipase D, but is predominantly expressed in spermatogonia and Sertoli cells, &Scaron, ¯, ADP-ribosylation factors (ARFs) are highly conserved guanine nucleotide-binding proteins that enhance the ADP-ribosyltransferase activity of cholera toxin |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Also known as: |
ARL4 Polyclonal Antibody |
| Other name: |
Anti-ARL4 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
ARL4 |
| Short name: |
Anti-ARL4 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-ARL4 (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
695 |
| Gene: |
ARL4A |
More about : ARL4A |
| Long gene name: |
ADP ribosylation factor like GTPase 4A |
| Synonyms gene: |
ARL4 |
| Synonyms gene name: |
ADP-ribosylation factor-like 4 ADP-ribosylation factor-like 4A |
| Locus: |
7p21, 3 |
| Discovery year: |
1999-06-02 |
| GenBank acession: |
U73960 |
| Entrez gene record: |
10124 |
| Pubmed identfication: |
22159419 |
| RefSeq identity: |
NM_005738 |
| Classification: |
ARF GTPase family |
| Havana BLAST/BLAT: |
OTTHUMG00000023374 |