| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
ARFGAP3 |
| Specificity: |
This antibody reacts specifically with ARFGAP3 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human ARFGAP3 |
| Gene ID: |
26286 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
11p11, ARFGAP2 (ADP-ribosylation factor GTPase-activating protein 2) and ARFGAP3 (ADP-ribosylation factor GTPase-activating protein 3) are GTPase-activating proteins (GAP) that are associated with the Golgi apparatus and interact with ADP-ribosylation factor 1 (ARF), ARFGAP2 and ARFGAP3 is stimulated by phosphoinosides and inhibited by phosphatidylcholine, ARFGAP2 and ARFGAP3 map to human chromosomes 20q13, Dissociation of the coat proteins is required for the fusion of these vesicles with target compartments, The activity of ARFGAP1, The genes encoding ARFGAP1, These proteins promote hydrolysis of ARF-bound GTP and are required for the dissociation of coat proteins from Golgi-derived membranes and vesicles, respectively, 2, 2 and 22q13, 33, ARFGAP1 (ADP-ribosylation factor GTPase-activating protein 1) |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Also known as: |
ARFGAP3 Polyclonal Antibody |
| Other name: |
Anti-ARFGAP3 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
ARFGAP3 |
| Short name: |
Anti-ARFGAP3 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-ARFGAP3 (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
661 |
| Gene: |
ARFGAP3 |
More about : ARFGAP3 |
| Long gene name: |
ADP ribosylation factor GTPase activating protein 3 |
| Synonyms gene: |
ARFGAP1 |
| Synonyms gene name: |
ADP-ribosylation factor GTPase activating protein 1 |
| Locus: |
22q13, 2 |
| Discovery year: |
1999-11-19 |
| GenBank acession: |
AK002083 |
| Entrez gene record: |
26286 |
| Pubmed identfication: |
10704287 11172815 |
| RefSeq identity: |
NM_014570 |
| Classification: |
ArfGAPs |
| Havana BLAST/BLAT: |
OTTHUMG00000150718 |