| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
ARFBP1 |
| Specificity: |
This antibody reacts specifically with ARFBP1 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human ARF6 |
| Gene ID: |
382 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
'Lys-61' and 'Lys-81', Also ubiquitinates the p53/TP53 tumor suppressor and core histones including H1, Binds to an upstream initiator-like sequence in the preprodynorphin gene, H2A, H2B, H3 and H4, May regulate abundance of CDC6 after DNA damage by polyubiquitinating and targeting CDC6 to degradation, Mediates monoubiquitination of DNA polymerase beta (POLB) at 'Lys-41', Regulates apoptosis by catalyzing the polyubiquitination and degradation of MCL1, Regulates neural differentiation and proliferation by catalyzing the polyubiquitination and degradation of MYCN, thereby playing a role in base-excision repair, E3 ubiquitin-protein ligase which mediates ubiquitination and subsequent proteasomal degradation of target proteins |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
ARF BP1, ARF-BP1, ARF-binding protein 1, BJ-HCC-24 tumor antigen, E3 ubiquitin protein ligase HUWE1, E3 ubiquitin-protein ligase HUWE1, HECT, HECT UBA and WWE domain containing protein 1, HECT domain protein LASU1, HUWE, HUWE1_HUMAN, HectH9, Homologous to E6AP carboxyl terminus homologous protein 9, Huwe1, Ib772, KIAA0312, KIAA1578, LASU1, Large structure of UREB1, MULE, Mcl 1 ubiquitin ligase E3, Mcl-1 ubiquitin ligase E3, UBA and WWE domain-containing protein 1, URE B1, URE-B1, URE-binding protein 1, UREB 1, UREB1, Upstream regulatory element-binding protein 1, ARF binding protein 1 |
| Also known as: |
ARFBP1 Polyclonal Antibody |
| Other name: |
Anti-ARFBP1 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
ARFBP1 |
| Short name: |
Anti-ARFBP1 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-ARFBP1 (polyclonal) |
| Alternative technique: |
polyclonals |