| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
DD1/AKR1C1/DD2 |
| Specificity: |
This antibody reacts specifically with DD1/AKR1C1/DD2 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human DD1 |
| Gene ID: |
1645 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
AKR1C3 and 3alpha-HSD are alternate designations for human DD3 (which is referred to as AKR1C18 in rodents), BABP or DDH2, CD, CHDR or AKR1C6 (in rodents), DD1 and DD2 are 20alpha-HSDs, DD1 and DD2 are ubiquitously expressed, DD3 is a unique enzyme that can specifically catalyze the dehydrogenation of trans-benzenedihydrodiol and trans-naphthalenedihydrodiol, DDH or DDH1, NADPH-dependent oxidoreductase that reduces 3-keto-5-dihydrosteroids to their tetrahydro products, The 20alpha-HSD catalyzes the reaction of progesterone to the inactive form 20alpha-hydroxyprogesterone, The 3alpha-HSD is a cytosolic, The multiple human cytosolic dihydrodiol dehydrogenases are involved in the metabolism of xenobiotics, and are responsible for the reduction of ketone-containing drugs by using NADH or NADPH as a cofactor, dDD, monomeric, pesticides and steroid hormones, such as polycyclic aromatic hydrocarbons, whereas DD3 and DD4 are the 3alpha-HSDs, whereas DD4 mRNA is restricted to the liver, while DD2 also can be designated AKR1C2, while DD4 also can be called AKR1C4, DD1 is also designated AKR1C1 |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
DD BABP DD2 HAKRD MCDR2 |
| Also known as: |
DD1/AKR1C1/DD2 Polyclonal Antibody |
| Other name: |
Anti-DD1/AKR1C1/DD2 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
DD1/AKR1C1/DD2 |
| Short name: |
Anti-DD1/AKR1C1/DD2 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-DD1/AKR1C1/DD2 (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
385 |
| Gene: |
AKR1C2 |
More about : AKR1C2 |
| Long gene name: |
aldo-keto reductase family 1 member C2 |
| Synonyms gene: |
DDH2 TDD |
| Synonyms gene name: |
3-alpha hydroxysteroid dehydrogenase, aldo-keto reductase family 1, bile acid binding protein, member C2 (dihydrodiol dehydrogenase 2, type III) testicular 17, 20-desmolase deficiency |
| Synonyms name: |
3-alpha hydroxysteroid dehydrogenase, bile acid binding protein, dihydrodiol dehydrogenase 2, type III |
| Locus: |
10p15, 1 |
| Discovery year: |
1994-09-14 |
| GenBank acession: |
L32592 |
| Entrez gene record: |
1646 |
| Pubmed identfication: |
9716498 21802064 |
| RefSeq identity: |
NM_001354 |
| Classification: |
Aldo-keto reductases |
| Havana BLAST/BLAT: |
OTTHUMG00000017584 |