| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
ABLIM3 |
| Specificity: |
This antibody reacts specifically with ABLIM3 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human ABLIM3 |
| Gene ID: |
22885 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
ABLIM1 binds to F-Actin through a dematin-like domain and is expressed in retina, ABLIM2 and ABLIM3 show highest expression in muscle and neuronal tissues, The gene encoding ABLIM1 maps to a region of chromosome 10 associated with frequent loss of heterozygosity in human tumors, There are four known isoforms of ABLIM1, They also have been shown to enhance STARS (striated muscle activator of Rho signaling) dependent activation of serum-response factor (SRF), and are localized on stress fibers, bind to F-Actin, brain and muscle tissue, thereby modulating transcription, thus identifying ABLIM1 as a candidate tumor suppressor gene, which conform to the LIM motif consensus sequence, The ABLIM1 protein has an N-terminal domain that contains four double zinc finger motifs |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
KIAA0843 |
| Also known as: |
ABLIM3 Polyclonal Antibody |
| Other name: |
Anti-ABLIM3 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
ABLIM3 |
| Short name: |
Anti-ABLIM3 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-ABLIM3 (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
29132 |
| Gene: |
ABLIM3 |
More about : ABLIM3 |
| Long gene name: |
actin binding LIM protein family member 3 |
| Synonyms gene name: |
actin binding LIM protein family, member 3 |
| Locus: |
5q32 |
| Discovery year: |
2004-01-22 |
| GenBank acession: |
AB020650 |
| Entrez gene record: |
22885 |
| RefSeq identity: |
NM_014945 |
| Classification: |
LIM domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000129932 |