| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
MAPK6/ERK3 |
| Specificity: |
This antibody reacts specifically with MAPK6/ERK3 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human MAPK6/ERK3 |
| Gene ID: |
5597 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Bcl-2 and caspase-3 during cell stress and damage induced by proteasome inhibition, Despite lacking a definitive nuclear localization sequence, ERK 3 constitutively localizes to the nucleus upon activation, Serum, The human ERK 3 gene maps to chromosome 15q21, also designated PRKM6 and p97MAPK), growth factors and phorbol esters can initiate ERK 3 signaling pathways, including extracellular-signal-related kinase 3 (ERK 3, p38 pathway activation-dependent upregulation of ERK 3 is independent of the status of p53, suggesting ERK 3 in part mediates intracellular defense or cell rescue, 2 and encodes a 721 amino acid protein, Mitogen-activated protein kinase (MAPK) signaling pathways involve closely related MAP kinases |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
ERK3 p97MAPK HsT17250 |
| Also known as: |
MAPK6/ERK3 Polyclonal Antibody |
| Other name: |
Anti-MAPK6/ERK3 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
MAPK6/ERK3 |
| Short name: |
Anti-MAPK6/ERK3 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-MAPK6/ERK3 (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
6879 |
| Gene: |
MAPK6 |
More about : MAPK6 |
| Long gene name: |
mitogen-activated protein kinase 6 |
| Synonyms gene: |
PRKM6 |
| Locus: |
15q21, 2 |
| Discovery year: |
1998-04-28 |
| GenBank acession: |
L77964 |
| Entrez gene record: |
5597 |
| Pubmed identfication: |
8875998 |
| RefSeq identity: |
NM_002748 |
| Classification: |
Mitogen-activated protein kinases |
| Havana BLAST/BLAT: |
OTTHUMG00000131891 |