| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
STRA6 |
| Specificity: |
This antibody reacts specifically with STRA6 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Subcellular locations: |
Extracellular |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human STRA6 |
| Gene ID: |
64220 |
| Applications: |
IF(IHC-P), FCM |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200), FCM(1:20-100) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Mutations in the gene encoding Stra6 cause Matthew-Wood Syndrome, Stra6 functions as a cell-surface receptor for the complex retinol-retinol binding protein (RBP/RBP4), Stra6 is broadly expressed, Stra6 removes retinol from RBP/RPB4 and transports it across the plasma membrane, The Stra6 gene maps to chromosome 15q24, This syndrome is characterized by anophtalmia, Ultimately increasing cellular retinol uptake from the retinol-RBP complex, also known as Spear Syndrome, lung and diaphragm, mild facial dysmorphism and malformations of the heart, multi-pass cell membrane protein, where it is metabolized, with 4 named isoforms that exist as a result of alternative splicing events, 1, STRA6 is a 667 amino acid |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
FLJ12541 |
| Also known as: |
STRA6 Polyclonal Antibody |
| Other name: |
Anti-STRA6 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
STRA6 |
| Short name: |
Anti-STRA6 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-STRA6 (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
30650 |
| Gene: |
STRA6 |
More about : STRA6 |
| Long gene name: |
stimulated by retinoic acid 6 |
| Synonyms gene name: |
stimulated by retinoic acid gene 6 homolog (mouse) stimulated by retinoic acid 6 homolog (mouse) |
| Synonyms name: |
retinol binding protein 4 receptor |
| Locus: |
15q24, 1 |
| Discovery year: |
2004-12-20 |
| GenBank acession: |
AF352728 |
| Entrez gene record: |
64220 |
| Pubmed identfication: |
17255476 17273977 |
| Havana BLAST/BLAT: |
OTTHUMG00000138998 |
| Locus Specific Databases: |
LOVD |