| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
TRIB1/GIG2 |
| Specificity: |
This antibody reacts specifically with TRIB1/GIG2 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human TRIB1/GIG2 |
| Gene ID: |
10221 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Expressed ubiquitously with highest expression in bone marrow, TRB-1 interacts with MAPK kinases and is thought to regulate the activation of MAP kinses, The gene encoding TRB-1 maps to human chromosome 8, houses more than 800 genes and is associated with a variety of diseases and malignancies, possibly controlling MAP kinase cascades, skeletal muscle and pancreas, thyroid gland, which consists of nearly 146 million base pairs, TRB-1 is a 372 amino acid protein that contains one protein kinase domain and belongs to the Ser/Thr protein kinase superfamily |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
C8FW GIG2 TRB1 |
| Also known as: |
TRIB1/GIG2 Polyclonal Antibody |
| Other name: |
Anti-TRIB1/GIG2 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
TRIB1/GIG2 |
| Short name: |
Anti-TRIB1/GIG2 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-tribbles homolog 1 (Drosophila)/GIG2 (polyclonal) |
| Alternative technique: |
polyclonals |
| Alternative to gene target: |
C8FW and GIG-2 and GIG2 and SKIP1 and TRB-1 and TRB1, TRIB1 and IDBG-35403 and ENSG00000173334 and 10221, TRIB1 and IDBG-644151 and ENSBTAG00000023179 and 521857, Trib1 and IDBG-144324 and ENSMUSG00000032501 and 211770, nuclei, this GO :0004672 and protein kinase activity and molecular function this GO :0004860 and protein kinase inhibitor activity and molecular function this GO :0005524 and ATP binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0006468 and protein phosphorylation and biological process this GO :0006469 and negative regulation of protein kinase activity and biological process this GO :0007254 and JNK cascade and biological process this GO :0008134 and transcription factor binding and molecular function this GO :0014912 and negative regulation of smooth muscle cell migration and biological process this GO :0016772 and transferase activity, this GO :0004672 : protein kinase activity, this GO :0004672 : protein kinase activity and also this GO :0004860 : protein kinase inhibitor activity and also this GO :0005524 : ATP binding and also this GO :0008134 : transcription factor binding and also this GO :0016772 : transferase activity, this GO :0004860 : protein kinase inhibitor activity, this GO :0005524 : ATP binding, this GO :0008134 : transcription factor binding, this GO :0016772 : transferase activity, this GO :0031434 : mitogen-activated protein kinase kinase binding, this GO :0031625 : ubiquitin protein ligase binding, this GO :0055106 : ubiquitin-protein ligase regulator activity, transferase activity, transferring phosphorus-containing groups, transferring phosphorus-containing groups and also this GO :0031434 : mitogen-activated protein kinase kinase binding and also this GO :0031625 : ubiquitin protein ligase binding and also this GO :0055106 : ubiquitin-protein ligase regulator activity, transferring phosphorus-containing groups and molecular function this GO :0031434 and mitogen-activated protein kinase kinase binding and molecular function this GO :0031625 and ubiquitin protein ligase binding and molecular function this GO :0031665 and negative regulation of lipopolysaccharide-mediated signaling pathway and biological process this GO :0032436 and positive regulation of proteasomal ubiquitin-dependent protein catabolic process and biological process this GO :0032496 and response to lipopolysaccharide and biological process this GO :0043405 and regulation of MAP kinase activity and biological process this GO :0043433 and negative regulation of sequence-specific DNA binding transcription factor activity and biological process this GO :0048662 and negative regulation of smooth muscle cell proliferation and biological process this GO :0055106 and ubiquitin-protein ligase regulator activity and molecular function, tribbles homolog 1 (Drosophila) |
| Identity: |
16891 |
| Gene: |
TRIB1 |
More about : TRIB1 |
| Long gene name: |
tribbles pseudokinase 1 |
| Synonyms gene name: |
tribbles homolog 1 (Drosophila) |
| Locus: |
8q24, 13 |
| Discovery year: |
2004-05-10 |
| GenBank acession: |
AF205437 |
| Entrez gene record: |
10221 |
| Pubmed identfication: |
9342215 16715410 |
| RefSeq identity: |
NM_025195 |
| Havana BLAST/BLAT: |
OTTHUMG00000165007 |