| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
ABL2 |
| Specificity: |
This antibody reacts specifically with ABL2 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human ABL2 |
| Gene ID: |
27 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
ABL2 is expressed in both normal and tumor cells, It is involved in translocation with the ETV6 gene in human leukemia and has an altered expression in several human carcinomas, The C-terminal domain of ABL2 contains two F-actin-binding sequences that perform a number of actions related to cell morphology and motility by interacting with actin filaments, The similarity of ABL1 and ABL2 includes the tyrosine kinase domains and extends amino-terminal to include the SH2 and SH3 domains, Two isoforms of ABL2 with different N-termini (1A and 1B) have been identified, ABL2 (or ARG) is a nonreceptor cytoplasmic tyrosine kinase which is closely related to but distinct from ABL1 |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
ARG |
| Also known as: |
ABL2 Polyclonal Antibody |
| Other name: |
Anti-ABL2 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
ABL2 |
| Short name: |
Anti-ABL2 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-v-abl Abelson murine leukemia viral oncogene homolog 2 (polyclonal) |
| Alternative technique: |
polyclonals |
| Alternative to gene target: |
ABL2 and IDBG-105099 and ENSG00000143322 and 27, ABLL and ARG, Abl2 and IDBG-200390 and ENSMUSG00000026596 and 11352, BT, Cytoplasm, this GO :0000287 and magnesium ion binding and molecular function this GO :0003785 and actin monomer binding and molecular function this GO :0004672 and protein kinase activity and molecular function this GO :0004713 and protein tyrosine kinase activity and molecular function this GO :0004715 and non-membrane spanning protein tyrosine kinase activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005524 and ATP binding and molecular function this GO :0005829 and cytosol and cellular component this GO :0006464 and cellular protein modification process and biological process this GO :0006468 and protein phosphorylation and biological process this GO :0007015 and actin filament organization and biological process this GO :0007155 and cell adhesion and biological process this GO :0007165 and signal transduction and biological process this GO :0007411 and axon guidance and biological process this GO :0010506 and regulation of autophagy and biological process this GO :0010976 and positive regulation of neuron projection development and biological process this GO :0015629 and actin cytoskeleton and cellular component this GO :0016772 and transferase activity, this GO :0000287 : magnesium ion binding, this GO :0000287 : magnesium ion binding and also this GO :0003785 : actin monomer binding and also this GO :0004672 : protein kinase activity and also this GO :0004713 : protein tyrosine kinase activity and also this GO :0004715 : non-membrane spanning protein tyrosine kinase activity and also this GO :0005515 : protein binding and also this GO :0005524 : ATP binding and also this GO :0016772 : transferase activity, this GO :0003785 : actin monomer binding, this GO :0004672 : protein kinase activity, this GO :0004713 : protein tyrosine kinase activity, this GO :0004715 : non-membrane spanning protein tyrosine kinase activity, this GO :0005515 : protein binding, this GO :0005524 : ATP binding, this GO :0016772 : transferase activity, this GO :0030145 : manganese ion binding, this GO :0051015 : actin filament binding, transferase activity, transferring phosphorus-containing groups, transferring phosphorus-containing groups and also this GO :0030145 : manganese ion binding and also this GO :0051015 : actin filament binding, transferring phosphorus-containing groups and molecular function this GO :0018108 and peptidyl-tyrosine phosphorylation and biological process this GO :0030100 and regulation of endocytosis and biological process this GO :0030145 and manganese ion binding and molecular function this GO :0030155 and regulation of cell adhesion and biological process this GO :0051015 and actin filament binding and molecular function this GO :0051017 and actin filament bundle assembly and biological process this GO :0051353 and positive regulation of oxidoreductase activity and biological process this GO :0071300 and cellular response to retinoic acid and biological process this GO :2000145 and regulation of cell motility and biological process this GO :2000249 and regulation of actin cytoskeleton reorganization and biological process, 62162 and IDBG-636736 and ENSBTAG00000015026 and 511845, v-abl Abelson murine leukemia viral oncogene homolog 2 |
| Identity: |
77 |
| Gene: |
ABL2 |
More about : ABL2 |
| Long gene name: |
ABL proto-oncogene 2, non-receptor tyrosine kinase |
| Synonyms gene: |
ABLL |
| Synonyms gene name: |
Abelson-related gene) v-abl Abelson murine leukemia viral oncogene homolog 2 c-abl oncogene 2, non-receptor tyrosine kinase , v-abl Abelson murine leukemia viral oncogene homolog 2 (arg |
| Synonyms name: |
Abelson-related gene |
| Locus: |
1q25, 2 |
| Discovery year: |
1986-01-01 |
| GenBank acession: |
M14904 |
| Entrez gene record: |
27 |
| Pubmed identfication: |
3787260 |
| RefSeq identity: |
NM_005158 |
| Classification: |
SH2 domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000035199 |