| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
EDR1/PHC1 |
| Specificity: |
This antibody reacts specifically with EDR1/PHC1 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human EDR1/PHC1 |
| Gene ID: |
1911 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Bmi-1, Existing as a homodimer, M33, MPc2, MPc3, Other constituent proteins involved in the PcG PRC1 complex are Mel-18, PHC1 contains one FCS-type zinc finger and a SAM (sterile alpha motif) domain, PHC1 is encoded by a gene located on human chromosome 12, RING1, Ring1b, Specifically, as well as several others, remodels chromatin and mediates monoubiquination of Histone H2A, the PcG PRC1 complex modifies histones, which encodes over 1, 004 amino acid nuclear protein that is a component of the PcG multiprotein PRC1 complex, 100 genes and comprises approximately 4, 5% of the human genome, PHC1 is a 1 |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
HPH1 RAE28 |
| Also known as: |
EDR1/PHC1 Polyclonal Antibody |
| Other name: |
Anti-EDR1/PHC1 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
EDR1/PHC1 |
| Short name: |
Anti-EDR1/PHC1 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-EDR1/PHC1 (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
3182 |
| Gene: |
PHC1 |
More about : PHC1 |
| Long gene name: |
polyhomeotic homolog 1 |
| Synonyms gene: |
EDR1 |
| Synonyms gene name: |
early development regulator 1 (homolog of polyhomeotic 1) polyhomeotic-like 1 (Drosophila) polyhomeotic homolog 1 (Drosophila) |
| Locus: |
12p13, 31 |
| Discovery year: |
1997-09-12 |
| GenBank acession: |
U89277 |
| Entrez gene record: |
1911 |
| Pubmed identfication: |
9121482 |
| RefSeq identity: |
NM_004426 |
| Classification: |
Sterile alpha motif domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000168275 |