| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
PDGFAA + PDGFBB |
| Specificity: |
This antibody reacts specifically with PDGFAA + PDGFBB |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human PDGFAA + PDGFBB |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Mutations in this gene are associated with meningioma, Oct 2008], Reciprocal translocations between chromosomes 22 and 7, The four members of this family are mitogenic factors for cells of mesenchymal origin and are characterized by a motif of eight cysteines, This gene product can exist either as a homodimer (PDGF-BB) or as a heterodimer with the platelet-derived growth factor alpha polypeptide (PDGF-AB), Two alternatively spliced transcript variants encoding different isoforms have been identified for this gene, [provided by RefSeq, are associated with a particular type of skin tumor called dermatofibrosarcoma protuberans resulting from unregulated expression of growth factor, at sites where this gene and that for COL1A1 are located, where the dimers are connected by disulfide bonds, The protein encoded by this gene is a member of the platelet-derived growth factor family |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
beta polypeptide oncogene SIS , Becaplermin , FLJ12858 , PDGF 1 , PDGF 2 , PDGF A , PDGF A chain , PDGF B , PDGF B chain , PDGF subunit B , PDGF-2 , PDGFB_HUMAN , Pdgfb , Platelet derived growth factor A chain precursor , Platelet derived growth factor B chain precursor , Platelet derived growth factor alpha polypeptide , Platelet derived growth factor beta polypeptide , Platelet derived growth factor beta polypeptide simian sarcoma viral v-sis oncogene homolog , Platelet-derived growth factor, Platelet-derived growth factor B chain , Platelet-derived growth factor beta polypeptide , Platelet-derived growth factor subunit B , Proto-oncogene c-Sis , SIS , SSV , c sis , c-sis , platelet-derived growth factor 2 , v sis platelet derived growth factor beta polypeptide simian sarcoma viral oncogene homolog |
| Also known as: |
PDGFAA + PDGFBB Polyclonal Antibody |
| Other name: |
Anti-PDGFAA + PDGFBB Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
PDGFAA + PDGFBB |
| Short name: |
Anti-PDGFAA + PDGFBB (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-PDGFAA and PDGFBB (polyclonal) |
| Alternative technique: |
polyclonals |