| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
SCN7A |
| Specificity: |
This antibody reacts specifically with SCN7A |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human SCN7A |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
During the propagation of an action potential, Na+ CP type VII Alpha (Sodium channel protein type 7 subunit alpha), Na+ CP type VII Alpha may function in the regulation of salt intake behavior and central sensing of body-fluid sodium levels, Primarily expressed in uterus and heart, Sodium channel protein cardiac and skeletal muscle subunit alpha and putative voltage-gated sodium channel subunit alpha Nax, The three glycoproteins that comprise the voltage-gated sodium channel proteins include a pore-forming Beta subunit, a noncovalently associated Beta 1 subunit and a disulfide-linked Beta 2 subunit, also known as SCN6A, is a 1682 amino acid multi-pass membrane protein that belongs to the sodium channel family, sodium channels allow an influx of sodium ions, which rapidly depolarize the cell, Voltage-gated sodium channels are selective ion channels that regulate the permeability of sodium ions in excitable cells |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
Nav2, 1 Nav2, 2 NaG |
| Also known as: |
SCN7A Polyclonal Antibody |
| Other name: |
Anti-SCN7A Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
SCN7A |
| Short name: |
Anti-SCN7A (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-SCN7A (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
10594 |
| Gene: |
SCN7A |
More about : SCN7A |
| Long gene name: |
sodium voltage-gated channel alpha subunit 7 |
| Synonyms gene: |
SCN6A |
| Synonyms gene name: |
alpha sodium channel, alpha sodium channel, alpha subunit sodium channel, sodium channel, type VI, type VII, type VII, type VII alpha subunit , voltage gated, voltage-gated, voltage-gated, voltage-gated |
| Locus: |
2q24, 3 |
| Discovery year: |
1992-04-10 |
| GenBank acession: |
M91556 |
| Entrez gene record: |
6332 |
| Pubmed identfication: |
10198179 |
| Havana BLAST/BLAT: |
OTTHUMG00000154078 |