| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
P2RX1 |
| Specificity: |
This antibody reacts specifically with P2RX1 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Subcellular locations: |
Extracellular |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human P2RX1 |
| Applications: |
IF(IHC-P), FCM |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200), FCM(1:20-100) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
P2X receptors are expressed in a wide variety of tissues, P2X1-P2X7, The P2X receptors may be involved in the onset of necrosis or apoptosis after prolonged exposure to high concentrations of extracellular ATP, The major function of the P2X receptors is to mediate synaptic transmissions between neurons and to other tissues via the binding of extracellular ATP, The seven P2X receptors, They are characterized by intracellular amino- and carboxy-termini, bladder, colon, form either homomeric or heteromeric channels or both, including neurons, pancreas, prostate, testis and ovary, which acts as a neurotransmitter, The P2X receptor family is comprised of ligand-gated ion channels that allow for the increased permeability of calcium into the cell in response to extracellular ATP |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
P2X1 |
| Also known as: |
P2RX1 Polyclonal Antibody |
| Other name: |
Anti-P2RX1 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
P2RX1 |
| Short name: |
Anti-P2RX1 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
1 (polyclonal), ALEXA Fluor 594, ligand-gated ion channel, antibody to-purinergic receptor P2X |
| Alternative technique: |
polyclonals |
| Alternative to gene target: |
1, P2RX1 and IDBG-18186 and ENSG00000108405 and 5023, P2RX1 and IDBG-633428 and ENSBTAG00000007169 and, P2X1, P2rx1 and IDBG-197393 and ENSMUSG00000020787 and 18436, glutamatergic and biological process this GO :0035590 and purinergic nucleotide receptor signaling pathway and biological process this GO :0042310 and vasoconstriction and biological process this GO :0043005 and neuron projection and cellular component this GO :0043234 and protein complex and cellular component this GO :0043270 and positive regulation of ion transport and biological process this GO :0045121 and membrane raft and cellular component this GO :0045211 and postsynaptic membrane and cellular component this GO :0046513 and ceramide biosynthetic process and biological process this GO :0051260 and protein homooli this GO merization and biological process this GO :0051291 and protein heterooli this GO merization and biological process this GO :0051924 and regulation of calcium ion transport and biological process this GO :0070588 and calcium ion transmembrane transport and biological process, ligand-gated ion channel, nuclei, this GO :0001614 and purinergic nucleotide receptor activity and molecular function this GO :0002554 and serotonin secretion by platelet and biological process this GO :0003056 and regulation of vascular smooth muscle contraction and biological process this GO :0004931 and extracellular ATP-gated cation channel activity and molecular function this GO :0005216 and ion channel activity and molecular function this GO :0005261 and cation channel activity and molecular function this GO :0005262 and calcium channel activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005524 and ATP binding and molecular function this GO :0005639 and integral component of nuclear inner membrane and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0005887 and integral component of plasma membrane and cellular component this GO :0006810 and transport and biological process this GO :0006811 and ion transport and biological process this GO :0006812 and cation transport and biological process this GO :0006919 and activation of cysteine-type endopeptidase activity involved in apoptotic process and biological process this GO :0006940 and regulation of smooth muscle contraction and biological process this GO :0007165 and signal transduction and biological process this GO :0007320 and insemination and biological process this GO :0007596 and blood coagulation and biological process this GO :0008144 and drug binding and molecular function this GO :0008217 and regulation of blood pressure and biological process this GO :0008270 and zinc ion binding and molecular function this GO :0010033 and response to organic substance and biological process this GO :0016020 and membrane and cellular component this GO :0019228 and neuronal action potential and biological process this GO :0019229 and regulation of vasoconstriction and biological process this GO :0030168 and platelet activation and biological process this GO :0031240 and external side of cell outer membrane and cellular component this GO :0033198 and response to ATP and biological process this GO :0034220 and ion transmembrane transport and biological process this GO :0035249 and synaptic transmission, this GO :0001614 : purinergic nucleotide receptor activity, this GO :0001614 : purinergic nucleotide receptor activity and also this GO :0004931 : extracellular ATP-gated cation channel activity and also this GO :0005216 : ion channel activity and also this GO :0005261 : cation channel activity and also this GO :0005262 : calcium channel activity and also this GO :0005515 : protein binding and also this GO :0005524 : ATP binding and also this GO :0008144 : drug binding and also this GO :0008270 : zinc ion binding, this GO :0004931 : extracellular ATP-gated cation channel activity, this GO :0005216 : ion channel activity, this GO :0005261 : cation channel activity, this GO :0005262 : calcium channel activity, this GO :0005515 : protein binding, this GO :0005524 : ATP binding, this GO :0008144 : drug binding, this GO :0008270 : zinc ion binding, zinc ion binding, purinergic receptor P2X |
| Identity: |
8533 |
| Gene: |
P2RX1 |
More about : P2RX1 |
| Long gene name: |
purinergic receptor P2X 1 |
| Synonyms gene name: |
1 , ligand-gated ion channel, purinergic receptor P2X |
| Locus: |
17p13, 3 |
| Discovery year: |
1997-01-16 |
| GenBank acession: |
X83688 |
| Entrez gene record: |
5023 |
| Pubmed identfication: |
8834001 |
| RefSeq identity: |
NM_002558 |
| Classification: |
Purinergic receptors P2X |
| Havana BLAST/BLAT: |
OTTHUMG00000177673 |