| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
TRPV3 |
| Specificity: |
This antibody reacts specifically with TRPV3 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Subcellular locations: |
Extracellular |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human TRPV3 |
| Applications: |
IF(IHC-P), FCM |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200), FCM(1:20-100) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Human TRPV3 is expressed in skin, In addition, It is abundantly expressed in kidney, TRPV3 associates with VR-1 and may modulate VR-1 activity, TRPV3 is co-expressed in dosal root ganglion neurons with VR-1, TRPV5 controls the rate-limiting step of vitamin D3-regulated Ca2+ reabsorption in kidney and intestine, The 729 amino acid TRPV5 (ECAC1) protein comprises six transmembrane domains, an N-linked glycosylation site and three ankyrin repeat regions, and at lower levels in testis, brain, capsaicin-insensitive TRPV3 is expressed at warm temperatures, colon and rectum, dorsal root ganglion, expression increases in response to noxious temperatures, including temperature sensation and vasoregulation Transcribed from a gene adjacent to VR-1, jejunum and pancreas, multiple potential phosphorylation sites, placenta, prostate, spinal cord and brain, the 5â, the thermal-sensitive, tongue, trigeminal ganglion, &euro, &trade, -flanking region of TRPV5 contains four putative vitamin D3-responsive elements, Transient receptor potential (TRP) proteins are cation-sensitive channels that modulate a myriad of cellular functions |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
VRL3 |
| Also known as: |
TRPV3 Polyclonal Antibody |
| Other name: |
Anti-TRPV3 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
TRPV3 |
| Short name: |
Anti-TRPV3 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-TRPV3 (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
18084 |
| Gene: |
TRPV3 |
More about : TRPV3 |
| Long gene name: |
transient receptor potential cation channel subfamily V member 3 |
| Synonyms gene name: |
member 3 , subfamily V, transient receptor potential cation channel |
| Locus: |
17p13, 2 |
| Discovery year: |
2002-07-05 |
| GenBank acession: |
AF514998 |
| Entrez gene record: |
162514 |
| Pubmed identfication: |
12016205 12077606 16382100 |
| RefSeq identity: |
NM_145068 |
| Classification: |
Ankyrin repeat domain containing Transient receptor potential cation channels |
| Havana BLAST/BLAT: |
OTTHUMG00000090695 |